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Year Number of Results
2010 2
2011 3
2012 3
2013 3
2014 3
2015 2
2016 3
2017 6
2018 3
2019 8
2020 1
2024 0

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36 results

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Page 1
New Dual Small Molecules for Alzheimer's Disease Therapy Combining Histamine H3 Receptor (H3R) Antagonism and Calcium Channels Blockade with Additional Cholinesterase Inhibition.
Malek R, Arribas RL, Palomino-Antolin A, Totoson P, Demougeot C, Kobrlova T, Soukup O, Iriepa I, Moraleda I, Diez-Iriepa D, Godyń J, Panek D, Malawska B, Głuch-Lutwin M, Mordyl B, Siwek A, Chabchoub F, Marco-Contelles J, Kiec-Kononowicz K, Egea J, de Los Ríos C, Ismaili L. Malek R, et al. Among authors: moraleda i. J Med Chem. 2019 Dec 26;62(24):11416-11422. doi: 10.1021/acs.jmedchem.9b00937. Epub 2019 Dec 5. J Med Chem. 2019. PMID: 31724859
Discovery of novel benzofuran-based compounds with neuroprotective and immunomodulatory properties for Alzheimer's disease treatment.
Montanari S, Mahmoud AM, Pruccoli L, Rabbito A, Naldi M, Petralla S, Moraleda I, Bartolini M, Monti B, Iriepa I, Belluti F, Gobbi S, Di Marzo V, Bisi A, Tarozzi A, Ligresti A, Rampa A. Montanari S, et al. Among authors: moraleda i. Eur J Med Chem. 2019 Sep 15;178:243-258. doi: 10.1016/j.ejmech.2019.05.080. Epub 2019 May 31. Eur J Med Chem. 2019. PMID: 31185414
Tackling neuroinflammation and cholinergic deficit in Alzheimer's disease: Multi-target inhibitors of cholinesterases, cyclooxygenase-2 and 15-lipoxygenase.
AlFadly ED, Elzahhar PA, Tramarin A, Elkazaz S, Shaltout H, Abu-Serie MM, Janockova J, Soukup O, Ghareeb DA, El-Yazbi AF, Rafeh RW, Bakkar NZ, Kobeissy F, Iriepa I, Moraleda I, Saudi MNS, Bartolini M, Belal ASF. AlFadly ED, et al. Among authors: moraleda i. Eur J Med Chem. 2019 Apr 1;167:161-186. doi: 10.1016/j.ejmech.2019.02.012. Epub 2019 Feb 8. Eur J Med Chem. 2019. PMID: 30771604
Donepezil + chromone + melatonin hybrids as promising agents for Alzheimer's disease therapy.
Pachón-Angona I, Refouvelet B, Andrýs R, Martin H, Luzet V, Iriepa I, Moraleda I, Diez-Iriepa D, Oset-Gasque MJ, Marco-Contelles J, Musilek K, Ismaili L. Pachón-Angona I, et al. Among authors: moraleda i. J Enzyme Inhib Med Chem. 2019 Dec;34(1):479-489. doi: 10.1080/14756366.2018.1545766. J Enzyme Inhib Med Chem. 2019. PMID: 30712420 Free PMC article.
Synthesis and biological assessment of KojoTacrines as new agents for Alzheimer's disease therapy.
Dgachi Y, Martin H, Malek R, Jun D, Janockova J, Sepsova V, Soukup O, Iriepa I, Moraleda I, Maalej E, Carreiras MC, Refouvelet B, Chabchoub F, Marco-Contelles J, Ismaili L. Dgachi Y, et al. Among authors: moraleda i. J Enzyme Inhib Med Chem. 2019 Dec;34(1):163-170. doi: 10.1080/14756366.2018.1538136. J Enzyme Inhib Med Chem. 2019. PMID: 30482062 Free PMC article.
36 results