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The effects of diet on occlusive coronary artery atherosclerosis and myocardial infarction in scavenger receptor class B, type 1/low-density lipoprotein receptor double knockout mice.
Fuller M, Dadoo O, Serkis V, Abutouk D, MacDonald M, Dhingani N, Macri J, Igdoura SA, Trigatti BL. Fuller M, et al. Among authors: igdoura sa. Arterioscler Thromb Vasc Biol. 2014 Nov;34(11):2394-403. doi: 10.1161/ATVBAHA.114.304200. Epub 2014 Sep 11. Arterioscler Thromb Vasc Biol. 2014. PMID: 25212235
Loss-of-function PCSK9 mutants evade the unfolded protein response sensor GRP78 and fail to induce endoplasmic reticulum stress when retained.
Lebeau P, Platko K, Al-Hashimi AA, Byun JH, Lhoták Š, Holzapfel N, Gyulay G, Igdoura SA, Cool DR, Trigatti B, Seidah NG, Austin RC. Lebeau P, et al. Among authors: igdoura sa. J Biol Chem. 2018 May 11;293(19):7329-7343. doi: 10.1074/jbc.RA117.001049. Epub 2018 Mar 28. J Biol Chem. 2018. PMID: 29593095 Free PMC article.
Sialidase down-regulation reduces non-HDL cholesterol, inhibits leukocyte transmigration, and attenuates atherosclerosis in ApoE knockout mice.
White EJ, Gyulay G, Lhoták Š, Szewczyk MM, Chong T, Fuller MT, Dadoo O, Fox-Robichaud AE, Austin RC, Trigatti BL, Igdoura SA. White EJ, et al. Among authors: igdoura sa. J Biol Chem. 2018 Sep 21;293(38):14689-14706. doi: 10.1074/jbc.RA118.004589. Epub 2018 Aug 10. J Biol Chem. 2018. PMID: 30097518 Free PMC article.
TDAG51 (T-Cell Death-Associated Gene 51) Is a Key Modulator of Vascular Calcification and Osteogenic Transdifferentiation of Arterial Smooth Muscle Cells.
Platko K, Lebeau PF, Gyulay G, Lhoták Š, MacDonald ME, Pacher G, Hyun Byun J, Boivin FJ, Igdoura SA, Cutz JC, Bridgewater D, Ingram AJ, Krepinsky JC, Austin RC. Platko K, et al. Among authors: igdoura sa. Arterioscler Thromb Vasc Biol. 2020 Jul;40(7):1664-1679. doi: 10.1161/ATVBAHA.119.313779. Epub 2020 May 21. Arterioscler Thromb Vasc Biol. 2020. PMID: 32434409 Free article.
Inhibitory Antibodies against PCSK9 Reduce Surface CD36 and Mitigate Diet-Induced Renal Lipotoxicity.
Byun JH, Lebeau PF, Platko K, Carlisle RE, Faiyaz M, Chen J, MacDonald ME, Makda Y, Yousof T, Lynn EG, Dickhout JG, Krepinsky JC, Weaver F, Igdoura SA, Seidah NG, Austin RC. Byun JH, et al. Among authors: igdoura sa. Kidney360. 2022 Apr 27;3(8):1394-1410. doi: 10.34067/KID.0007022021. eCollection 2022 Aug 25. Kidney360. 2022. PMID: 36176646 Free PMC article.
Extensive diet-induced atherosclerosis in scavenger receptor class B type 1-deficient mice is associated with substantial leukocytosis and elevated vascular cell adhesion molecule-1 expression in coronary artery endothelium.
Fuller MT, Dadoo O, Xiong T, Chivukula P, MacDonald ME, Lee SK, Austin RC, Igdoura SA, Trigatti BL. Fuller MT, et al. Among authors: igdoura sa. Front Physiol. 2023 Jan 12;13:1023397. doi: 10.3389/fphys.2022.1023397. eCollection 2022. Front Physiol. 2023. PMID: 36714321 Free PMC article.
54 results