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Limited mitochondrial permeabilization causes DNA damage and genomic instability in the absence of cell death.
Ichim G, Lopez J, Ahmed SU, Muthalagu N, Giampazolias E, Delgado ME, Haller M, Riley JS, Mason SM, Athineos D, Parsons MJ, van de Kooij B, Bouchier-Hayes L, Chalmers AJ, Rooswinkel RW, Oberst A, Blyth K, Rehm M, Murphy DJ, Tait SWG. Ichim G, et al. Mol Cell. 2015 Mar 5;57(5):860-872. doi: 10.1016/j.molcel.2015.01.018. Epub 2015 Feb 19. Mol Cell. 2015. PMID: 25702873 Free PMC article.
Widespread mitochondrial depletion via mitophagy does not compromise necroptosis.
Tait SW, Oberst A, Quarato G, Milasta S, Haller M, Wang R, Karvela M, Ichim G, Yatim N, Albert ML, Kidd G, Wakefield R, Frase S, Krautwald S, Linkermann A, Green DR. Tait SW, et al. Among authors: ichim g. Cell Rep. 2013 Nov 27;5(4):878-85. doi: 10.1016/j.celrep.2013.10.034. Epub 2013 Nov 21. Cell Rep. 2013. PMID: 24268776 Free PMC article.
Die another way--non-apoptotic mechanisms of cell death.
Tait SW, Ichim G, Green DR. Tait SW, et al. Among authors: ichim g. J Cell Sci. 2014 May 15;127(Pt 10):2135-44. doi: 10.1242/jcs.093575. J Cell Sci. 2014. PMID: 24833670 Free PMC article. Review.
Differential retrotranslocation of mitochondrial Bax and Bak.
Todt F, Cakir Z, Reichenbach F, Emschermann F, Lauterwasser J, Kaiser A, Ichim G, Tait SW, Frank S, Langer HF, Edlich F. Todt F, et al. Among authors: ichim g. EMBO J. 2015 Jan 2;34(1):67-80. doi: 10.15252/embj.201488806. Epub 2014 Nov 5. EMBO J. 2015. PMID: 25378477 Free PMC article.
Mito-priming as a method to engineer Bcl-2 addiction.
Lopez J, Bessou M, Riley JS, Giampazolias E, Todt F, Rochegüe T, Oberst A, Green DR, Edlich F, Ichim G, Tait SW. Lopez J, et al. Among authors: ichim g. Nat Commun. 2016 Feb 2;7:10538. doi: 10.1038/ncomms10538. Nat Commun. 2016. PMID: 26833356 Free PMC article.
Necroptosis: Fifty shades of RIPKs.
Ichim G, Tait SW. Ichim G, et al. Mol Cell Oncol. 2014 Nov 7;2(2):e965638. doi: 10.4161/23723548.2014.965638. eCollection 2015 Apr-Jun. Mol Cell Oncol. 2014. PMID: 27308415 Free PMC article.
Mitochondrial permeabilization engages NF-κB-dependent anti-tumour activity under caspase deficiency.
Giampazolias E, Zunino B, Dhayade S, Bock F, Cloix C, Cao K, Roca A, Lopez J, Ichim G, Proïcs E, Rubio-Patiño C, Fort L, Yatim N, Woodham E, Orozco S, Taraborrelli L, Peltzer N, Lecis D, Machesky L, Walczak H, Albert ML, Milling S, Oberst A, Ricci JE, Ryan KM, Blyth K, Tait SWG. Giampazolias E, et al. Among authors: ichim g. Nat Cell Biol. 2017 Sep;19(9):1116-1129. doi: 10.1038/ncb3596. Epub 2017 Aug 28. Nat Cell Biol. 2017. PMID: 28846096 Free PMC article.
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