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Extracellular truncated tau causes early presynaptic dysfunction associated with Alzheimer's disease and other tauopathies.
Florenzano F, Veronica C, Ciasca G, Ciotti MT, Pittaluga A, Olivero G, Feligioni M, Iannuzzi F, Latina V, Maria Sciacca MF, Sinopoli A, Milardi D, Pappalardo G, Marco S, Papi M, Atlante A, Bobba A, Borreca A, Calissano P, Amadoro G. Florenzano F, et al. Among authors: iannuzzi f. Oncotarget. 2017 Apr 22;8(39):64745-64778. doi: 10.18632/oncotarget.17371. eCollection 2017 Sep 12. Oncotarget. 2017. PMID: 29029390 Free PMC article.
Environmental training is beneficial to clinical symptoms and cortical presynaptic defects in mice suffering from experimental autoimmune encephalomyelitis.
Bonfiglio T, Olivero G, Vergassola M, Di Cesare Mannelli L, Pacini A, Iannuzzi F, Summa M, Bertorelli R, Feligioni M, Ghelardini C, Pittaluga A. Bonfiglio T, et al. Among authors: iannuzzi f. Neuropharmacology. 2019 Feb;145(Pt A):75-86. doi: 10.1016/j.neuropharm.2018.01.026. Epub 2018 Feb 2. Neuropharmacology. 2019. PMID: 29402503
Free d-aspartate triggers NMDA receptor-dependent cell death in primary cortical neurons and perturbs JNK activation, Tau phosphorylation, and protein SUMOylation in the cerebral cortex of mice lacking d-aspartate oxidase activity.
Nuzzo T, Feligioni M, Cristino L, Pagano I, Marcelli S, Iannuzzi F, Imperatore R, D'Angelo L, Petrella C, Carella M, Pollegioni L, Sacchi S, Punzo D, De Girolamo P, Errico F, Canu N, Usiello A. Nuzzo T, et al. Among authors: iannuzzi f. Exp Neurol. 2019 Jul;317:51-65. doi: 10.1016/j.expneurol.2019.02.014. Epub 2019 Feb 26. Exp Neurol. 2019. PMID: 30822420
54 results