Iacono G - Search Results

1

Increased H3K9 methylation and impaired expression of Protocadherins are associated with the cognitive dysfunctions of the Kleefstra syndrome.

Iacono G, Dubos A, Méziane H, Benevento M, Habibi E, Mandoli A, Riet F, Selloum M, Feil R, Zhou H, Kleefstra T, Kasri NN, van Bokhoven H, Herault Y, Stunnenberg HG. Iacono G, et al. Nucleic Acids Res. 2018 Jun 1;46(10):4950-4965. doi: 10.1093/nar/gky196. Nucleic Acids Res. 2018. PMID: 29554304 Free PMC article.

2

Histone Methylation by the Kleefstra Syndrome Protein EHMT1 Mediates Homeostatic Synaptic Scaling.

Benevento M, Iacono G, Selten M, Ba W, Oudakker A, Frega M, Keller J, Mancini R, Lewerissa E, Kleefstra T, Stunnenberg HG, Zhou H, van Bokhoven H, Nadif Kasri N. Benevento M, et al. Among authors: iacono g. Neuron. 2016 Jul 20;91(2):341-55. doi: 10.1016/j.neuron.2016.06.003. Epub 2016 Jun 30. Neuron. 2016. PMID: 27373831 Free article.

3

Ptchd1 deficiency induces excitatory synaptic and cognitive dysfunctions in mouse.

Ung DC, Iacono G, Méziane H, Blanchard E, Papon MA, Selten M, van Rhijn JR, Montjean R, Rucci J, Martin S, Fleet A, Birling MC, Marouillat S, Roepman R, Selloum M, Lux A, Thépault RA, Hamel P, Mittal K, Vincent JB, Dorseuil O, Stunnenberg HG, Billuart P, Nadif Kasri N, Hérault Y, Laumonnier F. Ung DC, et al. Among authors: iacono g. Mol Psychiatry. 2018 May;23(5):1356-1367. doi: 10.1038/mp.2017.39. Epub 2017 Apr 18. Mol Psychiatry. 2018. PMID: 28416808 Free PMC article.

4

Mouse models of 17q21.31 microdeletion and microduplication syndromes highlight the importance of Kansl1 for cognition.

Arbogast T, Iacono G, Chevalier C, Afinowi NO, Houbaert X, van Eede MC, Laliberte C, Birling MC, Linda K, Meziane H, Selloum M, Sorg T, Nadif Kasri N, Koolen DA, Stunnenberg HG, Henkelman RM, Kopanitsa M, Humeau Y, De Vries BBA, Herault Y. Arbogast T, et al. Among authors: iacono g. PLoS Genet. 2017 Jul 13;13(7):e1006886. doi: 10.1371/journal.pgen.1006886. eCollection 2017 Jul. PLoS Genet. 2017. PMID: 28704368 Free PMC article.

5

Integrated transcriptional analysis unveils the dynamics of cellular differentiation in the developing mouse hippocampus.

Iacono G, Benevento M, Dubos A, Herault Y, van Bokhoven H, Nadif Kasri N, Stunnenberg HG. Iacono G, et al. Sci Rep. 2017 Dec 22;7(1):18073. doi: 10.1038/s41598-017-18287-w. Sci Rep. 2017. PMID: 29273784 Free PMC article.

6

A new mouse model of ARX dup24 recapitulates the patients' behavioral and fine motor alterations.

Dubos A, Meziane H, Iacono G, Curie A, Riet F, Martin C, Loaëc N, Birling MC, Selloum M, Normand E, Pavlovic G, Sorg T, Stunnenberg HG, Chelly J, Humeau Y, Friocourt G, Hérault Y. Dubos A, et al. Among authors: iacono g. Hum Mol Genet. 2018 Jun 15;27(12):2138-2153. doi: 10.1093/hmg/ddy122. Hum Mol Genet. 2018. PMID: 29659809 Free PMC article.

7

Conditional depletion of intellectual disability and Parkinsonism candidate gene ATP6AP2 in fly and mouse induces cognitive impairment and neurodegeneration.

Dubos A, Castells-Nobau A, Meziane H, Oortveld MA, Houbaert X, Iacono G, Martin C, Mittelhaeuser C, Lalanne V, Kramer JM, Bhukel A, Quentin C, Slabbert J, Verstreken P, Sigrist SJ, Messaddeq N, Birling MC, Selloum M, Stunnenberg HG, Humeau Y, Schenck A, Herault Y. Dubos A, et al. Among authors: iacono g. Hum Mol Genet. 2015 Dec 1;24(23):6736-55. doi: 10.1093/hmg/ddv380. Epub 2015 Sep 16. Hum Mol Genet. 2015. PMID: 26376863 Free PMC article.

8

Dyrk1a gene dosage in glutamatergic neurons has key effects in cognitive deficits observed in mouse models of MRD7 and Down syndrome.

Brault V, Nguyen TL, Flores-Gutiérrez J, Iacono G, Birling MC, Lalanne V, Meziane H, Manousopoulou A, Pavlovic G, Lindner L, Selloum M, Sorg T, Yu E, Garbis SD, Hérault Y. Brault V, et al. Among authors: iacono g. PLoS Genet. 2021 Sep 29;17(9):e1009777. doi: 10.1371/journal.pgen.1009777. eCollection 2021 Sep. PLoS Genet. 2021. PMID: 34587162 Free PMC article.

9

Single-cell transcriptomics unveils gene regulatory network plasticity.

Iacono G, Massoni-Badosa R, Heyn H. Iacono G, et al. Genome Biol. 2019 Jun 4;20(1):110. doi: 10.1186/s13059-019-1713-4. Genome Biol. 2019. PMID: 31159854 Free PMC article.

10

bigSCale: an analytical framework for big-scale single-cell data.

Iacono G, Mereu E, Guillaumet-Adkins A, Corominas R, Cuscó I, Rodríguez-Esteban G, Gut M, Pérez-Jurado LA, Gut I, Heyn H. Iacono G, et al. Genome Res. 2018 Jun;28(6):878-890. doi: 10.1101/gr.230771.117. Epub 2018 May 3. Genome Res. 2018. PMID: 29724792 Free PMC article.

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