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Page 1
Neprilysin inhibition promotes corneal wound healing.
Genova RM, Meyer KJ, Anderson MG, Harper MM, Pieper AA. Genova RM, et al. Sci Rep. 2018 Sep 26;8(1):14385. doi: 10.1038/s41598-018-32773-9. Sci Rep. 2018. PMID: 30258206 Free PMC article.
(-)-P7C3-S243 Protects a Rat Model of Alzheimer's Disease From Neuropsychiatric Deficits and Neurodegeneration Without Altering Amyloid Deposition or Reactive Glia.
Voorhees JR, Remy MT, Cintrón-Pérez CJ, El Rassi E, Khan MZ, Dutca LM, Yin TC, McDaniel LN, Williams NS, Brat DJ, Pieper AA. Voorhees JR, et al. Biol Psychiatry. 2018 Oct 1;84(7):488-498. doi: 10.1016/j.biopsych.2017.10.023. Epub 2017 Nov 6. Biol Psychiatry. 2018. PMID: 29246437 Free PMC article.
The P7C3 class of neuroprotective compounds exerts antidepressant efficacy in mice by increasing hippocampal neurogenesis.
Walker AK, Rivera PD, Wang Q, Chuang JC, Tran S, Osborne-Lawrence S, Estill SJ, Starwalt R, Huntington P, Morlock L, Naidoo J, Williams NS, Ready JM, Eisch AJ, Pieper AA, Zigman JM. Walker AK, et al. Mol Psychiatry. 2015 Apr;20(4):500-8. doi: 10.1038/mp.2014.34. Epub 2014 Apr 22. Mol Psychiatry. 2015. PMID: 24751964 Free PMC article.
2-(2,5-Di-meth-oxy-phen-yl)-4,5-diphenyl-1-(prop-2-en-1-yl)-1H-imidazole.
Akkurt M, Mohamed SK, Marzouk AA, Abdelhamid AA, Santoyo-Gonzalez F. Akkurt M, et al. Acta Crystallogr Sect E Struct Rep Online. 2013 Jun 15;69(Pt 7):o1098-9. doi: 10.1107/S1600536813015936. eCollection 2013. Acta Crystallogr Sect E Struct Rep Online. 2013. PMID: 24046660 Free PMC article.