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CpG-free plasmids confer reduced inflammation and sustained pulmonary gene expression.
Hyde SC, Pringle IA, Abdullah S, Lawton AE, Davies LA, Varathalingam A, Nunez-Alonso G, Green AM, Bazzani RP, Sumner-Jones SG, Chan M, Li H, Yew NS, Cheng SH, Boyd AC, Davies JC, Griesenbach U, Porteous DJ, Sheppard DN, Munkonge FM, Alton EW, Gill DR. Hyde SC, et al. Nat Biotechnol. 2008 May;26(5):549-51. doi: 10.1038/nbt1399. Epub 2008 Apr 27. Nat Biotechnol. 2008. PMID: 18438402 Free article. Review.
Enhanced lung gene expression after aerosol delivery of concentrated pDNA/PEI complexes.
Davies LA, McLachlan G, Sumner-Jones SG, Ferguson D, Baker A, Tennant P, Gordon C, Vrettou C, Baker E, Zhu J, Alton EW, Collie DD, Porteous DJ, Hyde SC, Gill DR. Davies LA, et al. Among authors: hyde sc. Mol Ther. 2008 Jul;16(7):1283-90. doi: 10.1038/mt.2008.96. Epub 2008 May 20. Mol Ther. 2008. PMID: 18500249 Free article.
CpG-free plasmid expression cassettes for cystic fibrosis gene therapy.
Pringle IA, Hyde SC, Connolly MM, Lawton AE, Xu B, Nunez-Alonso G, Davies LA, Sumner-Jones SG, Gill DR. Pringle IA, et al. Among authors: hyde sc. Biomaterials. 2012 Oct;33(28):6833-42. doi: 10.1016/j.biomaterials.2012.06.009. Epub 2012 Jun 22. Biomaterials. 2012. PMID: 22727465
Rapid identification of novel functional promoters for gene therapy.
Pringle IA, Gill DR, Connolly MM, Lawton AE, Hewitt AM, Nunez-Alonso G, Cheng SH, Scheule RK, Davies LA, Hyde SC. Pringle IA, et al. Among authors: hyde sc. J Mol Med (Berl). 2012 Dec;90(12):1487-96. doi: 10.1007/s00109-012-0928-6. Epub 2012 Jul 6. J Mol Med (Berl). 2012. PMID: 22767241
115 results