Hyde RK - Search Results

1

Targeting binding partners of the CBFβ-SMMHC fusion protein for the treatment of inversion 16 acute myeloid leukemia.

Richter L, Wang Y, Hyde RK. Richter L, et al. Among authors: hyde rk. Oncotarget. 2016 Oct 4;7(40):66255-66266. doi: 10.18632/oncotarget.11357. Oncotarget. 2016. PMID: 27542261 Free PMC article. Review.

2

RUNX1 and CBFβ Mutations and Activities of Their Wild-Type Alleles in AML.

Hyde RK, Liu P, Friedman AD. Hyde RK, et al. Adv Exp Med Biol. 2017;962:265-282. doi: 10.1007/978-981-10-3233-2_17. Adv Exp Med Biol. 2017. PMID: 28299663 Review.

3

Chd7 deficiency delays leukemogenesis in mice induced by Cbfb-MYH11.

Zhen T, Kwon EM, Zhao L, Hsu J, Hyde RK, Lu Y, Alemu L, Speck NA, Liu PP. Zhen T, et al. Among authors: hyde rk. Blood. 2017 Nov 30;130(22):2431-2442. doi: 10.1182/blood-2017-04-780106. Epub 2017 Oct 10. Blood. 2017. PMID: 29018080 Free PMC article.

4

IL1RL1 is dynamically expressed on Cbfb-MYH11⁺ leukemia stem cells and promotes cell survival.

Wang Y, Richter L, Becker M, Amador C, Hyde RK. Wang Y, et al. Among authors: hyde rk. Sci Rep. 2019 Feb 11;9(1):1729. doi: 10.1038/s41598-018-38408-3. Sci Rep. 2019. PMID: 30742053 Free PMC article.

5

HDAC1 Is a Required Cofactor of CBFβ-SMMHC and a Potential Therapeutic Target in Inversion 16 Acute Myeloid Leukemia.

Richter LE, Wang Y, Becker ME, Coburn RA, Williams JT, Amador C, Hyde RK. Richter LE, et al. Among authors: hyde rk. Mol Cancer Res. 2019 Jun;17(6):1241-1252. doi: 10.1158/1541-7786.MCR-18-0922. Epub 2019 Feb 27. Mol Cancer Res. 2019. PMID: 30814129 Free PMC article.

6

Use of polymeric CXCR4 inhibitors as siRNA delivery vehicles for the treatment of acute myeloid leukemia.

Wang Y, Xie Y, Williams J, Hang Y, Richter L, Becker M, Amador C, Oupický D, Hyde RK. Wang Y, et al. Among authors: hyde rk. Cancer Gene Ther. 2020 Feb;27(1-2):45-55. doi: 10.1038/s41417-019-0095-9. Epub 2019 Apr 26. Cancer Gene Ther. 2020. PMID: 31028289

7

IL-33/IL1RL1 axis regulates cell survival through the p38 MAPK pathway in acute myeloid leukemia.

Wang Y, Luo H, Wei M, Becker M, Hyde RK, Gong Q. Wang Y, et al. Among authors: hyde rk. Leuk Res. 2020 Sep;96:106409. doi: 10.1016/j.leukres.2020.106409. Epub 2020 Jul 2. Leuk Res. 2020. PMID: 32652328

8

RUNX1 and CBFβ-SMMHC transactivate target genes together in abnormal myeloid progenitors for leukemia development.

Zhen T, Cao Y, Ren G, Zhao L, Hyde RK, Lopez G, Feng D, Alemu L, Zhao K, Liu PP. Zhen T, et al. Among authors: hyde rk. Blood. 2020 Nov 19;136(21):2373-2385. doi: 10.1182/blood.2020007747. Blood. 2020. PMID: 32929473 Free PMC article.

9

Integrating geriatric assessment and genetic profiling to personalize therapy selection in older adults with acute myeloid leukemia.

Bhatt VR, Wichman C, Al-Kadhimi ZS, Koll TT, Fisher AL, Mahato RI, Hyde RK, Berger A, Armitage JO, Holstein SA, Maness LJ, Gundabolu K. Bhatt VR, et al. Among authors: hyde rk. J Geriatr Oncol. 2022 Jul;13(6):871-874. doi: 10.1016/j.jgo.2022.04.005. Epub 2022 Apr 18. J Geriatr Oncol. 2022. PMID: 35450817 Free PMC article. Clinical Trial.

10

Accelerated leukemogenesis by truncated CBF beta-SMMHC defective in high-affinity binding with RUNX1.

Kamikubo Y, Zhao L, Wunderlich M, Corpora T, Hyde RK, Paul TA, Kundu M, Garrett L, Compton S, Huang G, Wolff L, Ito Y, Bushweller J, Mulloy JC, Liu PP. Kamikubo Y, et al. Among authors: hyde rk. Cancer Cell. 2010 May 18;17(5):455-68. doi: 10.1016/j.ccr.2010.03.022. Cancer Cell. 2010. PMID: 20478528 Free PMC article.

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