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Regulatory cell therapy in kidney transplantation (The ONE Study): a harmonised design and analysis of seven non-randomised, single-arm, phase 1/2A trials.
Sawitzki B, Harden PN, Reinke P, Moreau A, Hutchinson JA, Game DS, Tang Q, Guinan EC, Battaglia M, Burlingham WJ, Roberts ISD, Streitz M, Josien R, Böger CA, Scottà C, Markmann JF, Hester JL, Juerchott K, Braudeau C, James B, Contreras-Ruiz L, van der Net JB, Bergler T, Caldara R, Petchey W, Edinger M, Dupas N, Kapinsky M, Mutzbauer I, Otto NM, Öllinger R, Hernandez-Fuentes MP, Issa F, Ahrens N, Meyenberg C, Karitzky S, Kunzendorf U, Knechtle SJ, Grinyó J, Morris PJ, Brent L, Bushell A, Turka LA, Bluestone JA, Lechler RI, Schlitt HJ, Cuturi MC, Schlickeiser S, Friend PJ, Miloud T, Scheffold A, Secchi A, Crisalli K, Kang SM, Hilton R, Banas B, Blancho G, Volk HD, Lombardi G, Wood KJ, Geissler EK. Sawitzki B, et al. Among authors: hutchinson ja. Lancet. 2020 May 23;395(10237):1627-1639. doi: 10.1016/S0140-6736(20)30167-7. Lancet. 2020. PMID: 32446407 Free PMC article.
A cell-based approach to the minimization of immunosuppression in renal transplantation.
Hutchinson JA, Brem-Exner BG, Riquelme P, Roelen D, Schulze M, Ivens K, Grabensee B, Witzke O, Philipp T, Renders L, Humpe A, Sotnikova A, Matthäi M, Heumann A, Gövert F, Schulte T, Kabelitz D, Claas FH, Geissler EK, Kunzendorf U, Fändrich F. Hutchinson JA, et al. Transpl Int. 2008 Aug;21(8):742-54. doi: 10.1111/j.1432-2277.2008.00692.x. Epub 2008 Jul 10. Transpl Int. 2008. PMID: 18573141 Free article. Clinical Trial.
Human regulatory macrophages.
Hutchinson JA, Riquelme P, Geissler EK, Fändrich F. Hutchinson JA, et al. Methods Mol Biol. 2011;677:181-92. doi: 10.1007/978-1-60761-869-0_13. Methods Mol Biol. 2011. PMID: 20941611
Safety and feasibility of third-party multipotent adult progenitor cells for immunomodulation therapy after liver transplantation--a phase I study (MISOT-I).
Popp FC, Fillenberg B, Eggenhofer E, Renner P, Dillmann J, Benseler V, Schnitzbauer AA, Hutchinson J, Deans R, Ladenheim D, Graveen CA, Zeman F, Koller M, Hoogduijn MJ, Geissler EK, Schlitt HJ, Dahlke MH. Popp FC, et al. J Transl Med. 2011 Jul 28;9:124. doi: 10.1186/1479-5876-9-124. J Transl Med. 2011. PMID: 21798013 Free PMC article. Clinical Trial.
Cutting Edge: Immunological consequences and trafficking of human regulatory macrophages administered to renal transplant recipients.
Hutchinson JA, Riquelme P, Sawitzki B, Tomiuk S, Miqueu P, Zuhayra M, Oberg HH, Pascher A, Lützen U, Janssen U, Broichhausen C, Renders L, Thaiss F, Scheuermann E, Henze E, Volk HD, Chatenoud L, Lechler RI, Wood KJ, Kabelitz D, Schlitt HJ, Geissler EK, Fändrich F. Hutchinson JA, et al. J Immunol. 2011 Sep 1;187(5):2072-8. doi: 10.4049/jimmunol.1100762. Epub 2011 Jul 29. J Immunol. 2011. PMID: 21804023 Clinical Trial.
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