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Covalent bicyclization of protein complexes yields durable quaternary structures.
Chem. 2024 Feb 8;10(2):615-627. doi: 10.1016/j.chempr.2023.10.003.
Chem. 2024.
PMID: 38344167
Free PMC article.
Bicyclic Engineered Sortase A Performs Transpeptidation under Denaturing Conditions.
Kiehstaller S, Hutchins GH, Amore A, Gerber A, Ibrahim M, Hennig S, Neubacher S, Grossmann TN.
Kiehstaller S, et al. Among authors: hutchins gh.
Bioconjug Chem. 2023 Jun 21;34(6):1114-1121. doi: 10.1021/acs.bioconjchem.3c00151. Epub 2023 May 29.
Bioconjug Chem. 2023.
PMID: 37246906
Free PMC article.
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Covalent Proteomimetic Inhibitor of the Bacterial FtsQB Divisome Complex.
Paulussen FM, Schouten GK, Moertl C, Verheul J, Hoekstra I, Koningstein GM, Hutchins GH, Alkir A, Luirink RA, Geerke DP, van Ulsen P, den Blaauwen T, Luirink J, Grossmann TN.
Paulussen FM, et al. Among authors: hutchins gh.
J Am Chem Soc. 2022 Aug 24;144(33):15303-15313. doi: 10.1021/jacs.2c06304. Epub 2022 Aug 9.
J Am Chem Soc. 2022.
PMID: 35945166
Free PMC article.
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An expandable, modular de novo protein platform for precision redox engineering.
Hutchins GH, Noble CEM, Bunzel HA, Williams C, Dubiel P, Yadav SKN, Molinaro PM, Barringer R, Blackburn H, Hardy BJ, Parnell AE, Landau C, Race PR, Oliver TAA, Koder RL, Crump MP, Schaffitzel C, Oliveira ASF, Mulholland AJ, Anderson JLR.
Hutchins GH, et al.
Proc Natl Acad Sci U S A. 2023 Aug;120(31):e2306046120. doi: 10.1073/pnas.2306046120. Epub 2023 Jul 24.
Proc Natl Acad Sci U S A. 2023.
PMID: 37487099
Free PMC article.
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Antibodies and superantibodies in patients with chronic rhinosinusitis with nasal polyps.
Chen JB, James LK, Davies AM, Wu YB, Rimmer J, Lund VJ, Chen JH, McDonnell JM, Chan YC, Hutchins GH, Chang TW, Sutton BJ, Kariyawasam HH, Gould HJ.
Chen JB, et al. Among authors: hutchins gh.
J Allergy Clin Immunol. 2017 Apr;139(4):1195-1204.e11. doi: 10.1016/j.jaci.2016.06.066. Epub 2016 Sep 19.
J Allergy Clin Immunol. 2017.
PMID: 27658758
Free PMC article.
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