Hundsdoerfer P - Search Results

1

X-linked inhibitor of apoptosis protein represents a promising therapeutic target for relapsed/refractory ALL.

Carlet M, Schmelz K, Vergalli J, Herold T, Senft D, Jurinovic V, Hoffmann T, Proba J, Weichert N, Junghanß C, Roth M, Eschenburg G, Barz M, Henze G, Eckert C, Eggert A, Zuber J, Hundsdoerfer P, Jeremias I. Carlet M, et al. Among authors: hundsdoerfer p. EMBO Mol Med. 2023 Jan 11;15(1):e14557. doi: 10.15252/emmm.202114557. Epub 2022 Nov 23. EMBO Mol Med. 2023. PMID: 36416169 Free PMC article.

2

Long-term outcome after polychemotherapy and intensive local radiation therapy of high-grade osteosarcoma.

Hundsdoerfer P, Albrecht M, Rühl U, Fengler R, Kulozik AE, Henze G. Hundsdoerfer P, et al. Eur J Cancer. 2009 Sep;45(14):2447-51. doi: 10.1016/j.ejca.2009.06.006. Eur J Cancer. 2009. PMID: 19596190

3

XIAP expression is post-transcriptionally upregulated in childhood ALL and is associated with glucocorticoid response in T-cell ALL.

Hundsdoerfer P, Dietrich I, Schmelz K, Eckert C, Henze G. Hundsdoerfer P, et al. Pediatr Blood Cancer. 2010 Aug;55(2):260-6. doi: 10.1002/pbc.22541. Pediatr Blood Cancer. 2010. PMID: 20582956

4

Smac mimetic LBW242 sensitizes XIAP-overexpressing neuroblastoma cells for TNF-α-independent apoptosis.

Eschenburg G, Eggert A, Schramm A, Lode HN, Hundsdoerfer P. Eschenburg G, et al. Among authors: hundsdoerfer p. Cancer Res. 2012 May 15;72(10):2645-56. doi: 10.1158/0008-5472.CAN-11-4072. Epub 2012 Apr 9. Cancer Res. 2012. PMID: 22491673

5

Smac mimetic LCL161 supports neuroblastoma chemotherapy in a drug class-dependent manner and synergistically interacts with ALK inhibitor TAE684 in cells with ALK mutation F1174L.

Najem S, Langemann D, Appl B, Trochimiuk M, Hundsdoerfer P, Reinshagen K, Eschenburg G. Najem S, et al. Among authors: hundsdoerfer p. Oncotarget. 2016 Nov 8;7(45):72634-72653. doi: 10.18632/oncotarget.12055. Oncotarget. 2016. PMID: 27655666 Free PMC article.

6

Immunotherapy with the trifunctional anti-CD20 × anti-CD3 antibody FBTA05 in a patient with relapsed t(8;14)-positive post-transplant lymphoproliferative disease.

Kieslich A, Ruf P, Lindhofer H, Buhmann R, Eggert A, Hundsdoerfer P. Kieslich A, et al. Among authors: hundsdoerfer p. Leuk Lymphoma. 2017 Aug;58(8):1989-1992. doi: 10.1080/10428194.2016.1272687. Epub 2017 Jan 16. Leuk Lymphoma. 2017. PMID: 28093004 No abstract available.

7

Individualized risk assessment in neuroblastoma: does the tumoral metabolic activity on ¹²³I-MIBG SPECT predict the outcome?

Rogasch JMM, Hundsdoerfer P, Furth C, Wedel F, Hofheinz F, Krüger PC, Lode H, Brenner W, Eggert A, Amthauer H, Schatka I. Rogasch JMM, et al. Among authors: hundsdoerfer p. Eur J Nucl Med Mol Imaging. 2017 Dec;44(13):2203-2212. doi: 10.1007/s00259-017-3786-1. Epub 2017 Aug 14. Eur J Nucl Med Mol Imaging. 2017. PMID: 28808732

8

Sensitization of neuroblastoma for vincristine-induced apoptosis by Smac mimetic LCL161 is attended by G2 cell cycle arrest but is independent of NFκB, RIP1 and TNF-α.

Langemann D, Trochimiuk M, Appl B, Hundsdoerfer P, Reinshagen K, Eschenburg G. Langemann D, et al. Among authors: hundsdoerfer p. Oncotarget. 2017 Sep 23;8(50):87763-87772. doi: 10.18632/oncotarget.21193. eCollection 2017 Oct 20. Oncotarget. 2017. PMID: 29152118 Free PMC article.

9

Reactivating TP53 signaling by the novel MDM2 inhibitor DS-3032b as a therapeutic option for high-risk neuroblastoma.

Arnhold V, Schmelz K, Proba J, Winkler A, Wünschel J, Toedling J, Deubzer HE, Künkele A, Eggert A, Schulte JH, Hundsdoerfer P. Arnhold V, et al. Among authors: hundsdoerfer p. Oncotarget. 2017 Dec 18;9(2):2304-2319. doi: 10.18632/oncotarget.23409. eCollection 2018 Jan 5. Oncotarget. 2017. PMID: 29416773 Free PMC article.

10

Vincristine resistance in relapsed neuroblastoma can be efficiently overcome by Smac mimetic LCL161 treatment.

Frommann K, Appl B, Hundsdoerfer P, Reinshagen K, Eschenburg G. Frommann K, et al. Among authors: hundsdoerfer p. J Pediatr Surg. 2018 Oct;53(10):2059-2064. doi: 10.1016/j.jpedsurg.2018.01.012. Epub 2018 Jan 31. J Pediatr Surg. 2018. PMID: 29455885

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