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Deep thermal profiling for detection of functional proteoform groups.
Kurzawa N, Leo IR, Stahl M, Kunold E, Becher I, Audrey A, Mermelekas G, Huber W, Mateus A, Savitski MM, Jafari R. Kurzawa N, et al. Among authors: huber w. Nat Chem Biol. 2023 Aug;19(8):962-971. doi: 10.1038/s41589-023-01284-8. Epub 2023 Mar 20. Nat Chem Biol. 2023. PMID: 36941476 Free PMC article.
Identifying drug targets in tissues and whole blood with thermal-shift profiling.
Perrin J, Werner T, Kurzawa N, Rutkowska A, Childs DD, Kalxdorf M, Poeckel D, Stonehouse E, Strohmer K, Heller B, Thomson DW, Krause J, Becher I, Eberl HC, Vappiani J, Sevin DC, Rau CE, Franken H, Huber W, Faelth-Savitski M, Savitski MM, Bantscheff M, Bergamini G. Perrin J, et al. Among authors: huber w. Nat Biotechnol. 2020 Mar;38(3):303-308. doi: 10.1038/s41587-019-0388-4. Epub 2020 Jan 20. Nat Biotechnol. 2020. PMID: 31959954
Systematic discovery of biomolecular condensate-specific protein phosphorylation.
Sridharan S, Hernandez-Armendariz A, Kurzawa N, Potel CM, Memon D, Beltrao P, Bantscheff M, Huber W, Cuylen-Haering S, Savitski MM. Sridharan S, et al. Among authors: huber w. Nat Chem Biol. 2022 Oct;18(10):1104-1114. doi: 10.1038/s41589-022-01062-y. Epub 2022 Jul 21. Nat Chem Biol. 2022. PMID: 35864335 Free PMC article.
Proteogenomics refines the molecular classification of chronic lymphocytic leukemia.
Herbst SA, Vesterlund M, Helmboldt AJ, Jafari R, Siavelis I, Stahl M, Schitter EC, Liebers N, Brinkmann BJ, Czernilofsky F, Roider T, Bruch PM, Iskar M, Kittai A, Huang Y, Lu J, Richter S, Mermelekas G, Umer HM, Knoll M, Kolb C, Lenze A, Cao X, Österholm C, Wahnschaffe L, Herling C, Scheinost S, Ganzinger M, Mansouri L, Kriegsmann K, Kriegsmann M, Anders S, Zapatka M, Del Poeta G, Zucchetto A, Bomben R, Gattei V, Dreger P, Woyach J, Herling M, Müller-Tidow C, Rosenquist R, Stilgenbauer S, Zenz T, Huber W, Tausch E, Lehtiö J, Dietrich S. Herbst SA, et al. Among authors: huber w. Nat Commun. 2022 Oct 20;13(1):6226. doi: 10.1038/s41467-022-33385-8. Nat Commun. 2022. PMID: 36266272 Free PMC article.
979 results