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A pathogenic role for T cell-derived IL-22BP in inflammatory bowel disease.
Pelczar P, Witkowski M, Perez LG, Kempski J, Hammel AG, Brockmann L, Kleinschmidt D, Wende S, Haueis C, Bedke T, Witkowski M, Krasemann S, Steurer S, Booth CJ, Busch P, König A, Rauch U, Benten D, Izbicki JR, Rösch T, Lohse AW, Strowig T, Gagliani N, Flavell RA, Huber S. Pelczar P, et al. Among authors: huber s. Science. 2016 Oct 21;354(6310):358-362. doi: 10.1126/science.aah5903. Science. 2016. PMID: 27846573
IL-10 Receptor Signaling Is Essential for TR1 Cell Function In Vivo.
Brockmann L, Gagliani N, Steglich B, Giannou AD, Kempski J, Pelczar P, Geffken M, Mfarrej B, Huber F, Herkel J, Wan YY, Esplugues E, Battaglia M, Krebs CF, Flavell RA, Huber S. Brockmann L, et al. Among authors: huber s, huber f. J Immunol. 2017 Feb 1;198(3):1130-1141. doi: 10.4049/jimmunol.1601045. Epub 2016 Dec 21. J Immunol. 2017. PMID: 28003377 Free PMC article.
A Protective Function of IL-22BP in Ischemia Reperfusion and Acetaminophen-Induced Liver Injury.
Kleinschmidt D, Giannou AD, McGee HM, Kempski J, Steglich B, Huber FJ, Ernst TM, Shiri AM, Wegscheid C, Tasika E, Hübener P, Huber P, Bedke T, Steffens N, Agalioti T, Fuchs T, Noll J, Lotter H, Tiegs G, Lohse AW, Axelrod JH, Galun E, Flavell RA, Gagliani N, Huber S. Kleinschmidt D, et al. Among authors: huber p, huber fj, huber s. J Immunol. 2017 Dec 15;199(12):4078-4090. doi: 10.4049/jimmunol.1700587. Epub 2017 Nov 6. J Immunol. 2017. PMID: 29109123
Anti-inflammatory microenvironment of esophageal adenocarcinomas negatively impacts survival.
Karstens KF, Kempski J, Giannou AD, Pelczar P, Steglich B, Steurer S, Freiwald E, Woestemeier A, Konczalla L, Tachezy M, Reeh M, Bockhorn M, Perez D, Mann O, Lohse AW, Roesch T, Izbicki JR, Gagliani N, Huber S. Karstens KF, et al. Among authors: huber s. Cancer Immunol Immunother. 2020 Jun;69(6):1043-1056. doi: 10.1007/s00262-020-02517-8. Epub 2020 Feb 25. Cancer Immunol Immunother. 2020. PMID: 32100077 Free PMC article.
TGF-β signaling in Th17 cells promotes IL-22 production and colitis-associated colon cancer.
Perez LG, Kempski J, McGee HM, Pelzcar P, Agalioti T, Giannou A, Konczalla L, Brockmann L, Wahib R, Xu H, Vesely MCA, Soukou S, Steglich B, Bedke T, Manthey C, Seiz O, Diercks BP, Gnafakis S, Guse AH, Perez D, Izbicki JR, Gagliani N, Flavell RA, Huber S. Perez LG, et al. Among authors: huber s. Nat Commun. 2020 May 25;11(1):2608. doi: 10.1038/s41467-020-16363-w. Nat Commun. 2020. PMID: 32451418 Free PMC article.
IL22BP Mediates the Antitumor Effects of Lymphotoxin Against Colorectal Tumors in Mice and Humans.
Kempski J, Giannou AD, Riecken K, Zhao L, Steglich B, Lücke J, Garcia-Perez L, Karstens KF, Wöstemeier A, Nawrocki M, Pelczar P, Witkowski M, Nilsson S, Konczalla L, Shiri AM, Kempska J, Wahib R, Brockmann L, Huber P, Gnirck AC, Turner JE, Zazara DE, Arck PC, Stein A, Simon R, Daubmann A, Meiners J, Perez D, Strowig T, Koni P, Kruglov AA, Sauter G, Izbicki JR, Guse AH, Rösch T, Lohse AW, Flavell RA, Gagliani N, Huber S. Kempski J, et al. Among authors: huber p, huber s. Gastroenterology. 2020 Oct;159(4):1417-1430.e3. doi: 10.1053/j.gastro.2020.06.033. Epub 2020 Jun 22. Gastroenterology. 2020. PMID: 32585307 Free PMC article.
1,723 results