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Page 1
G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling.
Prentzell MT, Rehbein U, Cadena Sandoval M, De Meulemeester AS, Baumeister R, Brohée L, Berdel B, Bockwoldt M, Carroll B, Chowdhury SR, von Deimling A, Demetriades C, Figlia G; Genomics England Research Consortium; de Araujo MEG, Heberle AM, Heiland I, Holzwarth B, Huber LA, Jaworski J, Kedra M, Kern K, Kopach A, Korolchuk VI, van 't Land-Kuper I, Macias M, Nellist M, Palm W, Pusch S, Ramos Pittol JM, Reil M, Reintjes A, Reuter F, Sampson JR, Scheldeman C, Siekierska A, Stefan E, Teleman AA, Thomas LE, Torres-Quesada O, Trump S, West HD, de Witte P, Woltering S, Yordanov TE, Zmorzynska J, Opitz CA, Thedieck K. Prentzell MT, et al. Among authors: huber la. Cell. 2021 Feb 4;184(3):655-674.e27. doi: 10.1016/j.cell.2020.12.024. Epub 2021 Jan 25. Cell. 2021. PMID: 33497611 Free PMC article.
Subcellular fractionation.
de Araújo ME, Huber LA. de Araújo ME, et al. Among authors: huber la. Methods Mol Biol. 2007;357:73-85. doi: 10.1385/1-59745-214-9:73. Methods Mol Biol. 2007. PMID: 17172680
Polymorphisms in the gene regions of the adaptor complex LAMTOR2/LAMTOR3 and their association with breast cancer risk.
De Araujo ME, Erhart G, Buck K, Müller-Holzner E, Hubalek M, Fiegl H, Campa D, Canzian F, Eilber U, Chang-Claude J, Coassin S, Haun M, Kedenko L, Paulweber B, Reitsamer R, Himmel I, Flesch-Janys D, Lamina C, Kronenberg F, Huber LA, Kloss-Brandstätter A. De Araujo ME, et al. Among authors: huber la. PLoS One. 2013;8(1):e53768. doi: 10.1371/journal.pone.0053768. Epub 2013 Jan 16. PLoS One. 2013. PMID: 23341997 Free PMC article.
The late endosomal p14-MP1 (LAMTOR2/3) complex regulates focal adhesion dynamics during cell migration.
Schiefermeier N, Scheffler JM, de Araujo ME, Stasyk T, Yordanov T, Ebner HL, Offterdinger M, Munck S, Hess MW, Wickström SA, Lange A, Wunderlich W, Fässler R, Teis D, Huber LA. Schiefermeier N, et al. Among authors: huber la. J Cell Biol. 2014 May 26;205(4):525-40. doi: 10.1083/jcb.201310043. Epub 2014 May 19. J Cell Biol. 2014. PMID: 24841562 Free PMC article.
SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1.
Rebsamen M, Pochini L, Stasyk T, de Araújo ME, Galluccio M, Kandasamy RK, Snijder B, Fauster A, Rudashevskaya EL, Bruckner M, Scorzoni S, Filipek PA, Huber KV, Bigenzahn JW, Heinz LX, Kraft C, Bennett KL, Indiveri C, Huber LA, Superti-Furga G. Rebsamen M, et al. Among authors: huber la, huber kv. Nature. 2015 Mar 26;519(7544):477-81. doi: 10.1038/nature14107. Epub 2015 Jan 7. Nature. 2015. PMID: 25561175 Free PMC article.
Lysosomal signaling in control of degradation pathways.
Huber LA, Teis D. Huber LA, et al. Curr Opin Cell Biol. 2016 Apr;39:8-14. doi: 10.1016/j.ceb.2016.01.006. Epub 2016 Jan 28. Curr Opin Cell Biol. 2016. PMID: 26827287 Free article. Review.
Crystal structure of the human lysosomal mTORC1 scaffold complex and its impact on signaling.
de Araujo MEG, Naschberger A, Fürnrohr BG, Stasyk T, Dunzendorfer-Matt T, Lechner S, Welti S, Kremser L, Shivalingaiah G, Offterdinger M, Lindner HH, Huber LA, Scheffzek K. de Araujo MEG, et al. Among authors: huber la. Science. 2017 Oct 20;358(6361):377-381. doi: 10.1126/science.aao1583. Epub 2017 Sep 21. Science. 2017. PMID: 28935770
252 results