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Selection of cross-reactive T cells by commensal and food-derived yeasts drives cytotoxic TH1 cell responses in Crohn's disease.
Martini GR, Tikhonova E, Rosati E, DeCelie MB, Sievers LK, Tran F, Lessing M, Bergfeld A, Hinz S, Nikolaus S, Kümpers J, Matysiak A, Hofmann P, Saggau C, Schneiders S, Kamps AK, Jacobs G, Lieb W, Maul J, Siegmund B, Seegers B, Hinrichsen H, Oberg HH, Wesch D, Bereswill S, Heimesaat MM, Rupp J, Kniemeyer O, Brakhage AA, Brunke S, Hube B, Aden K, Franke A, Iliev ID, Scheffold A, Schreiber S, Bacher P. Martini GR, et al. Among authors: hube b. Nat Med. 2023 Oct;29(10):2602-2614. doi: 10.1038/s41591-023-02556-5. Epub 2023 Sep 25. Nat Med. 2023. PMID: 37749331 Free PMC article.
Antigen specificity and cross-reactivity drive functionally diverse anti-Aspergillus fumigatus T cell responses in cystic fibrosis.
Schwarz C, Eschenhagen P, Schmidt H, Hohnstein T, Iwert C, Grehn C, Roehmel J, Steinke E, Stahl M, Lozza L, Tikhonova E, Rosati E, Stervbo U, Babel N, Mainz JG, Wisplinghoff H, Ebel F, Jia LJ, Blango MG, Hortschansky P, Brunke S, Hube B, Brakhage AA, Kniemeyer O, Scheffold A, Bacher P. Schwarz C, et al. Among authors: hube b. J Clin Invest. 2023 Mar 1;133(5):e161593. doi: 10.1172/JCI161593. J Clin Invest. 2023. PMID: 36701198 Free PMC article.
Ecological Niche-Inspired Genome Mining Leads to the Discovery of Crop-Protecting Nonribosomal Lipopeptides Featuring a Transient Amino Acid Building Block.
Götze S, Vij R, Burow K, Thome N, Urbat L, Schlosser N, Pflanze S, Müller R, Hänsch VG, Schlabach K, Fazlikhani L, Walther G, Dahse HM, Regestein L, Brunke S, Hube B, Hertweck C, Franken P, Stallforth P. Götze S, et al. Among authors: hube b. J Am Chem Soc. 2023 Feb 1;145(4):2342-2353. doi: 10.1021/jacs.2c11107. Epub 2023 Jan 20. J Am Chem Soc. 2023. PMID: 36669196 Free PMC article.
Organ-on-chip models for infectious disease research.
Alonso-Roman R, Mosig AS, Figge MT, Papenfort K, Eggeling C, Schacher FH, Hube B, Gresnigt MS. Alonso-Roman R, et al. Among authors: hube b. Nat Microbiol. 2024 Apr;9(4):891-904. doi: 10.1038/s41564-024-01645-6. Epub 2024 Mar 25. Nat Microbiol. 2024. PMID: 38528150 Review.
Alpha1-antitrypsin impacts innate host-pathogen interactions with Candida albicans by stimulating fungal filamentation.
Jaeger M, Dietschmann A, Austermeier S, Dinçer S, Porschitz P, Vornholz L, Maas RJA, Sprenkeler EGG, Ruland J, Wirtz S, Azam T, Joosten LAB, Hube B, Netea MG, Dinarello CA, Gresnigt MS. Jaeger M, et al. Among authors: hube b. Virulence. 2024 Dec;15(1):2333367. doi: 10.1080/21505594.2024.2333367. Epub 2024 Apr 10. Virulence. 2024. PMID: 38515333 Free PMC article.
Competitive fungal commensalism mitigates candidiasis pathology.
Sekeresova Kralova J, Donic C, Dassa B, Livyatan I, Jansen PM, Ben-Dor S, Fidel L, Trzebanski S, Narunsky-Haziza L, Asraf O, Brenner O, Dafni H, Jona G, Boura-Halfon S, Stettner N, Segal E, Brunke S, Pilpel Y, Straussman R, Zeevi D, Bacher P, Hube B, Shlezinger N, Jung S. Sekeresova Kralova J, et al. Among authors: hube b. J Exp Med. 2024 May 6;221(5):e20231686. doi: 10.1084/jem.20231686. Epub 2024 Mar 18. J Exp Med. 2024. PMID: 38497819
292 results