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High-content screening identifies a small molecule that restores AP-4-dependent protein trafficking in neuronal models of AP-4-associated hereditary spastic paraplegia.
Saffari A, Brechmann B, Böger C, Saber WA, Jumo H, Whye D, Wood D, Wahlster L, Alecu JE, Ziegler M, Scheffold M, Winden K, Hubbs J, Buttermore ED, Barrett L, Borner GHH, Davies AK, Ebrahimi-Fakhari D, Sahin M. Saffari A, et al. Among authors: hubbs j. Nat Commun. 2024 Jan 17;15(1):584. doi: 10.1038/s41467-023-44264-1. Nat Commun. 2024. PMID: 38233389 Free PMC article.
ALDH5A1-deficient iPSC-derived excitatory and inhibitory neurons display cell type specific alterations.
Afshar-Saber W, Teaney NA, Winden KD, Jumo H, Shi X, McGinty G, Hubbs J, Chen C, Tokatly Latzer I, Gasparoli F, Ebrahimi-Fakhari D, Buttermore ED, Roullet JB, Pearl PL, Sahin M. Afshar-Saber W, et al. Among authors: hubbs j. Neurobiol Dis. 2024 Jan;190:106386. doi: 10.1016/j.nbd.2023.106386. Epub 2023 Dec 16. Neurobiol Dis. 2024. PMID: 38110041 Free PMC article.
High-Content Small Molecule Screen Identifies a Novel Compound That Restores AP-4-Dependent Protein Trafficking in Neuronal Models of AP-4-Associated Hereditary Spastic Paraplegia.
Saffari A, Brechmann B, Boeger C, Saber WA, Jumo H, Whye D, Wood D, Wahlster L, Alecu J, Ziegler M, Scheffold M, Winden K, Hubbs J, Buttermore E, Barrett L, Borner G, Davies A, Sahin M, Ebrahimi-Fakhari D. Saffari A, et al. Among authors: hubbs j. Res Sq [Preprint]. 2023 Jun 12:rs.3.rs-3036166. doi: 10.21203/rs.3.rs-3036166/v1. Res Sq. 2023. PMID: 37398196 Free PMC article. Updated. Preprint.
Translating a Global Emission-Reduction Framework for Subnational Climate Action: A Case Study from the State of Georgia.
Brown MA, Beasley B, Atalay F, Cobb KM, Dwiveldi P, Hubbs J, Iwaniek DM, Mani S, Matisoff D, Mohan JE, Mullen J, Oxman M, Rochberg D, Rodgers M, Shepherd M, Simmons R, Taylor L, Toktay LB. Brown MA, et al. Among authors: hubbs j. Environ Manage. 2021 Feb;67(2):205-227. doi: 10.1007/s00267-020-01406-1. Epub 2021 Jan 15. Environ Manage. 2021. PMID: 33449138 Free PMC article.
Itch suppression in mice and dogs by modulation of spinal α2 and α3GABAA receptors.
Ralvenius WT, Neumann E, Pagani M, Acuña MA, Wildner H, Benke D, Fischer N, Rostaher A, Schwager S, Detmar M, Frauenknecht K, Aguzzi A, Hubbs JL, Rudolph U, Favrot C, Zeilhofer HU. Ralvenius WT, et al. Among authors: hubbs jl. Nat Commun. 2018 Aug 13;9(1):3230. doi: 10.1038/s41467-018-05709-0. Nat Commun. 2018. PMID: 30104684 Free PMC article.
55 results