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Distinct subcellular localisation of intramyocellular lipids and reduced PKCε/PKCθ activity preserve muscle insulin sensitivity in exercise-trained mice.
Gaspar RC, Lyu K, Hubbard BT, Leitner BP, Luukkonen PK, Hirabara SM, Sakuma I, Nasiri A, Zhang D, Kahn M, Cline GW, Pauli JR, Perry RJ, Petersen KF, Shulman GI. Gaspar RC, et al. Among authors: hubbard bt. Diabetologia. 2023 Mar;66(3):567-578. doi: 10.1007/s00125-022-05838-8. Epub 2022 Dec 1. Diabetologia. 2023. PMID: 36456864
Multiomics analysis identifies oxidative phosphorylation as a cancer vulnerability arising from myristoylation inhibition.
Beauchamp E, Gamma JM, Cromwell CR, Moussa EW, Pain R, Kostiuk MA, Acevedo-Morantes C, Iyer A, Yap M, Vincent KM, Postovit LM, Julien O, Hubbard BP, Mackey JR, Berthiaume LG. Beauchamp E, et al. Among authors: hubbard bp. J Transl Med. 2024 May 7;22(1):431. doi: 10.1186/s12967-024-05150-6. J Transl Med. 2024. PMID: 38715059 Free PMC article.
Reversible and irreversible inhibitors of coronavirus Nsp15 endoribonuclease.
Chen J, Farraj RA, Limonta D, Tabatabaei Dakhili SA, Kerek EM, Bhattacharya A, Reformat FM, Mabrouk OM, Brigant B, Pfeifer TA, McDermott MT, Ussher JR, Hobman TC, Glover JNM, Hubbard BP. Chen J, et al. Among authors: hubbard bp. J Biol Chem. 2023 Nov;299(11):105341. doi: 10.1016/j.jbc.2023.105341. Epub 2023 Oct 11. J Biol Chem. 2023. PMID: 37832873 Free PMC article.
Siglec-6 mediates the uptake of extracellular vesicles through a noncanonical glycolipid binding pocket.
Schmidt EN, Lamprinaki D, McCord KA, Joe M, Sojitra M, Waldow A, Nguyen J, Monyror J, Kitova EN, Mozaneh F, Guo XY, Jung J, Enterina JR, Daskhan GC, Han L, Krysler AR, Cromwell CR, Hubbard BP, West LJ, Kulka M, Sipione S, Klassen JS, Derda R, Lowary TL, Mahal LK, Riddell MR, Macauley MS. Schmidt EN, et al. Among authors: hubbard bp. Nat Commun. 2023 Apr 22;14(1):2327. doi: 10.1038/s41467-023-38030-6. Nat Commun. 2023. PMID: 37087495 Free PMC article.
Prediction for 2-Year Vision Outcomes Using Early Morphologic and Functional Responses in the Comparison of Age-related Macular Degeneration Treatments Trials.
Xue K, Hua P, Maguire MG, Daniel E, Jaffe GJ, Grunwald JE, Ying GS; Comparison of Age-Related Macular Degeneration Treatments Trials (CATT) Research Group. Xue K, et al. Ophthalmol Retina. 2023 Jul;7(7):564-572. doi: 10.1016/j.oret.2023.02.008. Epub 2023 Feb 19. Ophthalmol Retina. 2023. PMID: 36803692 Clinical Trial.
346 results