Huang Z - Search Results

1

Prediction of treatment response to antipsychotic drugs for precision medicine approach to schizophrenia: randomized trials and multiomics analysis.

Guo LK, Su Y, Zhang YY, Yu H, Lu Z, Li WQ, Yang YF, Xiao X, Yan H, Lu TL, Li J, Liao YD, Kang ZW, Wang LF, Li Y, Li M, Liu B, Huang HL, Lv LX, Yao Y, Tan YL, Breen G, Everall I, Wang HX, Huang Z, Zhang D, Yue WH. Guo LK, et al. Among authors: huang hl, huang z. Mil Med Res. 2023 Jun 2;10(1):24. doi: 10.1186/s40779-023-00459-7. Mil Med Res. 2023. PMID: 37269009 Free PMC article.

2

ERG3 potassium channel-mediated suppression of neuronal intrinsic excitability and prevention of seizure generation in mice.

Xiao K, Sun Z, Jin X, Ma W, Song Y, Lai S, Chen Q, Fan M, Zhang J, Yue W, Huang Z. Xiao K, et al. Among authors: huang z. J Physiol. 2018 Oct;596(19):4729-4752. doi: 10.1113/JP275970. Epub 2018 Sep 7. J Physiol. 2018. PMID: 30016551 Free PMC article.

3

Association Study of KCNH7 Polymorphisms and Individual Responses to Risperidone Treatment in Schizophrenia.

Wang X, Su Y, Yan H, Huang Z, Huang Y, Yue W. Wang X, et al. Among authors: huang z, huang y. Front Psychiatry. 2019 Aug 30;10:633. doi: 10.3389/fpsyt.2019.00633. eCollection 2019. Front Psychiatry. 2019. PMID: 31543842 Free PMC article.

4

Closed-state inactivation and pore-blocker modulation mechanisms of human Ca_V2.2.

Dong Y, Gao Y, Xu S, Wang Y, Yu Z, Li Y, Li B, Yuan T, Yang B, Zhang XC, Jiang D, Huang Z, Zhao Y. Dong Y, et al. Among authors: huang z. Cell Rep. 2021 Nov 2;37(5):109931. doi: 10.1016/j.celrep.2021.109931. Cell Rep. 2021. PMID: 34731621 Free article.

5

Structural basis for Na_V1.7 inhibition by pore blockers.

Zhang J, Shi Y, Huang Z, Li Y, Yang B, Gong J, Jiang D. Zhang J, et al. Among authors: huang z. Nat Struct Mol Biol. 2022 Dec;29(12):1208-1216. doi: 10.1038/s41594-022-00860-1. Epub 2022 Nov 24. Nat Struct Mol Biol. 2022. PMID: 36424527

6

Structure of human Na_V1.6 channel reveals Na⁺ selectivity and pore blockade by 4,9-anhydro-tetrodotoxin.

Li Y, Yuan T, Huang B, Zhou F, Peng C, Li X, Qiu Y, Yang B, Zhao Y, Huang Z, Jiang D. Li Y, et al. Among authors: huang b, huang z. Nat Commun. 2023 Feb 23;14(1):1030. doi: 10.1038/s41467-023-36766-9. Nat Commun. 2023. PMID: 36823201 Free PMC article.

7

Prediction of drug efficacy from transcriptional profiles with deep learning.

Zhu J, Wang J, Wang X, Gao M, Guo B, Gao M, Liu J, Yu Y, Wang L, Kong W, An Y, Liu Z, Sun X, Huang Z, Zhou H, Zhang N, Zheng R, Xie Z. Zhu J, et al. Among authors: huang z. Nat Biotechnol. 2021 Nov;39(11):1444-1452. doi: 10.1038/s41587-021-00946-z. Epub 2021 Jun 17. Nat Biotechnol. 2021. PMID: 34140681

8

Identification and characterization of benzo[d]oxazol-2(3H)-one derivatives as the first potent and selective small-molecule inhibitors of chromodomain protein CDYL.

Yang L, Liu Y, Fan M, Zhu G, Jin H, Liang J, Liu Z, Huang Z, Zhang L. Yang L, et al. Among authors: huang z. Eur J Med Chem. 2019 Nov 15;182:111656. doi: 10.1016/j.ejmech.2019.111656. Epub 2019 Aug 31. Eur J Med Chem. 2019. PMID: 31494467

9

Multiple machine learning methods aided virtual screening of Na_V 1.5 inhibitors.

Kong W, Huang W, Peng C, Zhang B, Duan G, Ma W, Huang Z. Kong W, et al. Among authors: huang w, huang z. J Cell Mol Med. 2023 Jan;27(2):266-276. doi: 10.1111/jcmm.17652. Epub 2022 Dec 27. J Cell Mol Med. 2023. PMID: 36573431 Free PMC article.

10

Prediction and Optimization of Na_V1.7 Sodium Channel Inhibitors Based on Machine Learning and Simulated Annealing.

Kong W, Tu X, Huang W, Yang Y, Xie Z, Huang Z. Kong W, et al. Among authors: huang w, huang z. J Chem Inf Model. 2020 Jun 22;60(6):2739-2753. doi: 10.1021/acs.jcim.9b01180. Epub 2020 Jun 4. J Chem Inf Model. 2020. PMID: 32421318

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