Huang Y - Search Results

1

Hybrid peptide-polyketide natural products: biosynthesis and prospects towards engineering novel molecules.

Du L, Cheng YQ, Ingenhorst G, Tang GL, Huang Y, Shen B. Du L, et al. Among authors: huang y. Genet Eng (N Y). 2003;25:227-67. doi: 10.1007/978-1-4615-0073-5_11. Genet Eng (N Y). 2003. PMID: 15260241 Review. No abstract available.

2

Characterization of the Ketosynthase and Acyl Carrier Protein Domains at the LnmI Nonribosomal Peptide Synthetase-Polyketide Synthase Interface for Leinamycin Biosynthesis.

Huang Y, Tang GL, Pan G, Chang CY, Shen B. Huang Y, et al. Org Lett. 2016 Sep 2;18(17):4288-91. doi: 10.1021/acs.orglett.6b02033. Epub 2016 Aug 19. Org Lett. 2016. PMID: 27541042 Free PMC article.

3

Leinamycin E1 acting as an anticancer prodrug activated by reactive oxygen species.

Huang SX, Yun BS, Ma M, Basu HS, Church DR, Ingenhorst G, Huang Y, Yang D, Lohman JR, Tang GL, Ju J, Liu T, Wilding G, Shen B. Huang SX, et al. Among authors: huang y. Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):8278-83. doi: 10.1073/pnas.1506761112. Epub 2015 Jun 8. Proc Natl Acad Sci U S A. 2015. PMID: 26056295 Free PMC article.

4

Biosynthesis of thiocarboxylic acid-containing natural products.

Dong LB, Rudolf JD, Kang D, Wang N, He CQ, Deng Y, Huang Y, Houk KN, Duan Y, Shen B. Dong LB, et al. Among authors: huang y. Nat Commun. 2018 Jun 18;9(1):2362. doi: 10.1038/s41467-018-04747-y. Nat Commun. 2018. PMID: 29915173 Free PMC article.

5

Bifunctional acyltransferase/decarboxylase LnmK as the missing link for beta-alkylation in polyketide biosynthesis.

Liu T, Huang Y, Shen B. Liu T, et al. Among authors: huang y. J Am Chem Soc. 2009 May 27;131(20):6900-1. doi: 10.1021/ja9012134. J Am Chem Soc. 2009. PMID: 19405532 Free PMC article.

6

Characterization of the lnmKLM genes unveiling key intermediates for β-alkylation in leinamycin biosynthesis.

Huang Y, Huang SX, Ju J, Tang G, Liu T, Shen B. Huang Y, et al. Among authors: huang sx. Org Lett. 2011 Feb 4;13(3):498-501. doi: 10.1021/ol102838y. Epub 2010 Dec 30. Org Lett. 2011. PMID: 21192727 Free PMC article.

7

Characterization of LnmO as a pathway-specific Crp/Fnr-type positive regulator for leinamycin biosynthesis in Streptomyces atroolivaceus and its application for titer improvement.

Huang Y, Yang D, Pan G, Tang GL, Shen B. Huang Y, et al. Appl Microbiol Biotechnol. 2016 Dec;100(24):10555-10562. doi: 10.1007/s00253-016-7864-2. Epub 2016 Oct 5. Appl Microbiol Biotechnol. 2016. PMID: 27704182 Free PMC article.

8

Ribosome engineering and fermentation optimization leads to overproduction of tiancimycin A, a new enediyne natural product from Streptomyces sp. CB03234.

Liu L, Pan J, Wang Z, Yan X, Yang D, Zhu X, Shen B, Duan Y, Huang Y. Liu L, et al. Among authors: huang y. J Ind Microbiol Biotechnol. 2018 Mar;45(3):141-151. doi: 10.1007/s10295-018-2014-8. Epub 2018 Feb 2. J Ind Microbiol Biotechnol. 2018. PMID: 29396746 Free PMC article.

9

A 3-hydroxy-3-methylglutaryl-CoA synthase-based probe for the discovery of the acyltransferase-less type I polyketide synthases.

Liang H, Jiang L, Jiang Q, Shi J, Xiang J, Yan X, Zhu X, Zhao L, Shen B, Duan Y, Huang Y. Liang H, et al. Among authors: huang y. Environ Microbiol. 2019 Nov;21(11):4270-4282. doi: 10.1111/1462-2920.14787. Epub 2019 Sep 8. Environ Microbiol. 2019. PMID: 31435987

10

Strain Prioritization and Genome Mining for Enediyne Natural Products.

Yan X, Ge H, Huang T, Hindra, Yang D, Teng Q, Crnovčić I, Li X, Rudolf JD, Lohman JR, Gansemans Y, Zhu X, Huang Y, Zhao LX, Jiang Y, Van Nieuwerburgh F, Rader C, Duan Y, Shen B. Yan X, et al. Among authors: huang t, huang y. mBio. 2016 Dec 20;7(6):e02104-16. doi: 10.1128/mBio.02104-16. mBio. 2016. PMID: 27999165 Free PMC article.

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