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Vaccination with a structure-based stabilized version of malarial antigen Pfs48/45 elicits ultra-potent transmission-blocking antibody responses.
McLeod B, Mabrouk MT, Miura K, Ravichandran R, Kephart S, Hailemariam S, Pham TP, Semesi A, Kucharska I, Kundu P, Huang WC, Johnson M, Blackstone A, Pettie D, Murphy M, Kraft JC, Leaf EM, Jiao Y, van de Vegte-Bolmer M, van Gemert GJ, Ramjith J, King CR, MacGill RS, Wu Y, Lee KK, Jore MM, King NP, Lovell JF, Julien JP. McLeod B, et al. Among authors: huang wc. Immunity. 2022 Sep 13;55(9):1680-1692.e8. doi: 10.1016/j.immuni.2022.07.015. Epub 2022 Aug 16. Immunity. 2022. PMID: 35977542 Free PMC article.
A malaria vaccine adjuvant based on recombinant antigen binding to liposomes.
Huang WC, Deng B, Lin C, Carter KA, Geng J, Razi A, He X, Chitgupi U, Federizon J, Sun B, Long CA, Ortega J, Dutta S, King CR, Miura K, Lee SM, Lovell JF. Huang WC, et al. Nat Nanotechnol. 2018 Dec;13(12):1174-1181. doi: 10.1038/s41565-018-0271-3. Epub 2018 Oct 8. Nat Nanotechnol. 2018. PMID: 30297818 Free PMC article.
Lyophilized, antigen-bound liposomes with reduced MPLA and enhanced thermostability.
Mabrouk MT, Huang WC, Deng B, Li-Purcell N, Seffouh A, Ortega J, Ekin Atilla-Gokcumen G, Long CA, Miura K, Lovell JF. Mabrouk MT, et al. Among authors: huang wc. Int J Pharm. 2020 Nov 15;589:119843. doi: 10.1016/j.ijpharm.2020.119843. Epub 2020 Sep 2. Int J Pharm. 2020. PMID: 32890653 Free PMC article.
2,110 results