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Transcriptomics and Network Pharmacology Reveal the Protective Effect of Chaiqin Chengqi Decoction on Obesity-Related Alcohol-Induced Acute Pancreatitis via Oxidative Stress and PI3K/Akt Signaling Pathway.
Yang X, Yao L, Yuan M, Zhang X, Jakubowska MA, Ferdek PE, Dai L, Yang J, Jin T, Deng L, Fu X, Du D, Liu T, Criddle DN, Sutton R, Huang W, Xia Q. Yang X, et al. Among authors: huang w. Front Pharmacol. 2022 Jun 8;13:896523. doi: 10.3389/fphar.2022.896523. eCollection 2022. Front Pharmacol. 2022. PMID: 35754467 Free PMC article.
Chaiqin chengqi decoction alleviates severity of acute pancreatitis via inhibition of TLR4 and NLRP3 inflammasome: Identification of bioactive ingredients via pharmacological sub-network analysis and experimental validation.
Wen Y, Han C, Liu T, Wang R, Cai W, Yang J, Liang G, Yao L, Shi N, Fu X, Deng L, Sutton R, Windsor JA, Hong J, Phillips AR, Du D, Huang W, Xia Q. Wen Y, et al. Among authors: huang w. Phytomedicine. 2020 Dec;79:153328. doi: 10.1016/j.phymed.2020.153328. Epub 2020 Sep 1. Phytomedicine. 2020. PMID: 33007730 Free article.
Chaiqin chengqi decoction ameliorates acute pancreatitis in mice via inhibition of neuron activation-mediated acinar cell SP/NK1R signaling pathways.
Han C, Du D, Wen Y, Li J, Wang R, Jin T, Yang J, Shi N, Jiang K, Deng L, Fu X, Mukherjee R, Windsor JA, Hong J, Phillips AR, Sutton R, Huang W, Liu T, Xia Q. Han C, et al. Among authors: huang w. J Ethnopharmacol. 2021 Jun 28;274:114029. doi: 10.1016/j.jep.2021.114029. Epub 2021 Mar 14. J Ethnopharmacol. 2021. PMID: 33731310 Free article.
Stress Hyperglycemia Is Independently Associated with Persistent Organ Failure in Acute Pancreatitis.
Yang X, Zhang R, Jin T, Zhu P, Yao L, Li L, Cai W, Mukherjee R, Du D, Fu X, Xue J, Martina R, Liu T, Pendharkar S, Phillips AR, Singh VK, Sutton R, Windsor JA, Deng L, Xia Q, Huang W. Yang X, et al. Among authors: huang w. Dig Dis Sci. 2022 May;67(5):1879-1889. doi: 10.1007/s10620-021-06982-8. Epub 2021 May 3. Dig Dis Sci. 2022. PMID: 33939149 Free PMC article.
A microRNA checkpoint for Ca2+ signaling and overload in acute pancreatitis.
Du W, Liu G, Shi N, Tang D, Ferdek PE, Jakubowska MA, Liu S, Zhu X, Zhang J, Yao L, Sang X, Zou S, Liu T, Mukherjee R, Criddle DN, Zheng X, Xia Q, Berggren PO, Huang W, Sutton R, Tian Y, Huang W, Fu X. Du W, et al. Among authors: huang w. Mol Ther. 2022 Apr 6;30(4):1754-1774. doi: 10.1016/j.ymthe.2022.01.033. Epub 2022 Jan 22. Mol Ther. 2022. PMID: 35077860 Free PMC article.
Temporal metabolic trajectory analyzed by LC-MS/MS based targeted metabolomics in acute pancreatitis pathogenesis and Chaiqin Chengqi decoction therapy.
Huang Y, Wen Y, Wang R, Hu L, Yang J, Yang J, Pu Q, Han C, Cai W, Peng Y, Wang Y, Jiang H, Hong J, Phillips AR, Fu X, Huang W, Xia Q, Du D. Huang Y, et al. Among authors: huang w. Phytomedicine. 2022 May;99:153996. doi: 10.1016/j.phymed.2022.153996. Epub 2022 Feb 17. Phytomedicine. 2022. PMID: 35231826
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