Huang SN - Search Results

1

DNA and RNA Cleavage Complexes and Repair Pathway for TOP3B RNA- and DNA-Protein Crosslinks.

Saha S, Sun Y, Huang SN, Baechler SA, Pongor LS, Agama K, Jo U, Zhang H, Tse-Dinh YC, Pommier Y. Saha S, et al. Among authors: huang sn. Cell Rep. 2020 Dec 29;33(13):108569. doi: 10.1016/j.celrep.2020.108569. Cell Rep. 2020. PMID: 33378676 Free PMC article.

2

Mutagenic processing of ribonucleotides in DNA by yeast topoisomerase I.

Kim N, Huang SN, Williams JS, Li YC, Clark AB, Cho JE, Kunkel TA, Pommier Y, Jinks-Robertson S. Kim N, et al. Among authors: huang sn. Science. 2011 Jun 24;332(6037):1561-4. doi: 10.1126/science.1205016. Science. 2011. PMID: 21700875 Free PMC article.

3

Tyrosyl-DNA Phosphodiesterase 1 (Tdp1) inhibitors.

Huang SN, Pommier Y, Marchand C. Huang SN, et al. Expert Opin Ther Pat. 2011 Sep;21(9):1285-92. doi: 10.1517/13543776.2011.604314. Expert Opin Ther Pat. 2011. PMID: 21843105 Free PMC article. Review.

4

Roles of eukaryotic topoisomerases in transcription, replication and genomic stability.

Pommier Y, Sun Y, Huang SN, Nitiss JL. Pommier Y, et al. Among authors: huang sn. Nat Rev Mol Cell Biol. 2016 Nov;17(11):703-721. doi: 10.1038/nrm.2016.111. Epub 2016 Sep 21. Nat Rev Mol Cell Biol. 2016. PMID: 27649880 Free PMC article. Review.

5

Topoisomerase I-mediated cleavage at unrepaired ribonucleotides generates DNA double-strand breaks.

Huang SN, Williams JS, Arana ME, Kunkel TA, Pommier Y. Huang SN, et al. EMBO J. 2017 Feb 1;36(3):361-373. doi: 10.15252/embj.201592426. Epub 2016 Dec 8. EMBO J. 2017. PMID: 27932446 Free PMC article.

6

The dominant role of proofreading exonuclease activity of replicative polymerase ε in cellular tolerance to cytarabine (Ara-C).

Tsuda M, Terada K, Ooka M, Kobayashi K, Sasanuma H, Fujisawa R, Tsurimoto T, Yamamoto J, Iwai S, Kadoda K, Akagawa R, Huang SN, Pommier Y, Sale JE, Takeda S, Hirota K. Tsuda M, et al. Among authors: huang sn. Oncotarget. 2017 May 16;8(20):33457-33474. doi: 10.18632/oncotarget.16508. Oncotarget. 2017. PMID: 28380422 Free PMC article.

7

Effects of camptothecin or TOP1 overexpression on genetic stability in Saccharomyces cerevisiae.

Sloan R, Huang SN, Pommier Y, Jinks-Robertson S. Sloan R, et al. Among authors: huang sn. DNA Repair (Amst). 2017 Nov;59:69-75. doi: 10.1016/j.dnarep.2017.09.004. Epub 2017 Sep 18. DNA Repair (Amst). 2017. PMID: 28961461 Free PMC article.

8

Mitochondrial tyrosyl-DNA phosphodiesterase 2 and its TDP2^S short isoform.

Huang SN, Dalla Rosa I, Michaels SA, Tulumello DV, Agama K, Khiati S, Jean SR, Baechler SA, Factor VM, Varma S, Murai J, Miller Jenkins LM, Kelley SO, Pommier Y. Huang SN, et al. EMBO Rep. 2018 Mar;19(3):e42139. doi: 10.15252/embr.201642139. Epub 2018 Feb 9. EMBO Rep. 2018. PMID: 29438979 Free PMC article.

9

Probing the evolutionary conserved residues Y204, F259, S400 and W590 that shape the catalytic groove of human TDP1 for 3'- and 5'-phosphodiester-DNA bond cleavage.

Kiselev E, Dexheimer TS, Marchand C, Huang SN, Pommier Y. Kiselev E, et al. Among authors: huang sn. DNA Repair (Amst). 2018 Jun-Jul;66-67:64-71. doi: 10.1016/j.dnarep.2018.05.001. Epub 2018 May 2. DNA Repair (Amst). 2018. PMID: 29747024 Free PMC article.

10

TDP1 suppresses mis-joining of radiomimetic DNA double-strand breaks and cooperates with Artemis to promote optimal nonhomologous end joining.

Kawale AS, Akopiants K, Valerie K, Ruis B, Hendrickson EA, Huang SN, Pommier Y, Povirk LF. Kawale AS, et al. Among authors: huang sn. Nucleic Acids Res. 2018 Sep 28;46(17):8926-8939. doi: 10.1093/nar/gky694. Nucleic Acids Res. 2018. PMID: 30113698 Free PMC article.

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