Huang S - Search Results

1

Structure-guided engineering of adenine base editor with minimized RNA off-targeting activity.

Li J, Yu W, Huang S, Wu S, Li L, Zhou J, Cao Y, Huang X, Qiao Y. Li J, et al. Among authors: huang s, huang x. Nat Commun. 2021 Apr 16;12(1):2287. doi: 10.1038/s41467-021-22519-z. Nat Commun. 2021. PMID: 33863894 Free PMC article.

2

BE-PLUS: a new base editing tool with broadened editing window and enhanced fidelity.

Jiang W, Feng S, Huang S, Yu W, Li G, Yang G, Liu Y, Zhang Y, Zhang L, Hou Y, Chen J, Chen J, Huang X. Jiang W, et al. Among authors: huang s, huang x. Cell Res. 2018 Aug;28(8):855-861. doi: 10.1038/s41422-018-0052-4. Epub 2018 Jun 6. Cell Res. 2018. PMID: 29875396 Free PMC article.

3

Efficient generation of mouse models of human diseases via ABE- and BE-mediated base editing.

Liu Z, Lu Z, Yang G, Huang S, Li G, Feng S, Liu Y, Li J, Yu W, Zhang Y, Chen J, Sun Q, Huang X. Liu Z, et al. Among authors: huang s, huang x. Nat Commun. 2018 Jun 14;9(1):2338. doi: 10.1038/s41467-018-04768-7. Nat Commun. 2018. PMID: 29904106 Free PMC article.

4

Correction of the Marfan Syndrome Pathogenic FBN1 Mutation by Base Editing in Human Cells and Heterozygous Embryos.

Zeng Y, Li J, Li G, Huang S, Yu W, Zhang Y, Chen D, Chen J, Liu J, Huang X. Zeng Y, et al. Among authors: huang s, huang x. Mol Ther. 2018 Nov 7;26(11):2631-2637. doi: 10.1016/j.ymthe.2018.08.007. Epub 2018 Aug 14. Mol Ther. 2018. PMID: 30166242 Free PMC article.

5

Efficient base editing in G/C-rich regions to model androgen insensitivity syndrome.

Li J, Liu Z, Huang S, Wang X, Li G, Xu Y, Yu W, Chen S, Zhang Y, Ma H, Ke Z, Chen J, Sun Q, Huang X. Li J, et al. Among authors: huang s, huang x. Cell Res. 2019 Feb;29(2):174-176. doi: 10.1038/s41422-018-0133-4. Epub 2019 Jan 3. Cell Res. 2019. PMID: 30607018 Free PMC article. No abstract available.

6

Base-Editing-Mediated R17H Substitution in Histone H3 Reveals Methylation-Dependent Regulation of Yap Signaling and Early Mouse Embryo Development.

Yang G, Zhou C, Wang R, Huang S, Wei Y, Yang X, Liu Y, Li J, Lu Z, Ying W, Li X, Jing N, Huang X, Yang H, Qiao Y. Yang G, et al. Among authors: huang s, huang x. Cell Rep. 2019 Jan 8;26(2):302-312.e4. doi: 10.1016/j.celrep.2018.12.046. Cell Rep. 2019. PMID: 30625312 Free article.

7

Developing ABEmax-NG with Precise Targeting and Expanded Editing Scope to Model Pathogenic Splice Site Mutations In Vivo.

Huang S, Liao Z, Li X, Liu Z, Li G, Li J, Lu Z, Zhang Y, Li X, Ma X, Sun Q, Huang X. Huang S, et al. Among authors: huang x. iScience. 2019 May 31;15:640-648. doi: 10.1016/j.isci.2019.05.008. Epub 2019 May 11. iScience. 2019. PMID: 31130518 Free PMC article.

8

Efficient Generation of Pathogenic A-to-G Mutations in Human Tripronuclear Embryos via ABE-Mediated Base Editing.

Li G, Liu X, Huang S, Zeng Y, Yang G, Lu Z, Zhang Y, Ma X, Wang L, Huang X, Liu J. Li G, et al. Among authors: huang s, huang x. Mol Ther Nucleic Acids. 2019 Sep 6;17:289-296. doi: 10.1016/j.omtn.2019.05.021. Epub 2019 Jun 5. Mol Ther Nucleic Acids. 2019. PMID: 31279230 Free PMC article.

9

Increasing the targeting scope and efficiency of base editing with Proxy-BE strategy.

Liu Y, Li G, Yang G, Gu H, Huang S, Yu W, Qin G, Liu X, Zhou F, Huang X, Wei Y. Liu Y, et al. Among authors: huang s, huang x. FEBS Lett. 2020 Apr;594(8):1319-1328. doi: 10.1002/1873-3468.13719. Epub 2019 Dec 29. FEBS Lett. 2020. PMID: 31837228 Free article.

10

Efficient Gene Silencing by Adenine Base Editor-Mediated Start Codon Mutation.

Wang X, Liu Z, Li G, Dang L, Huang S, He L, Ma Y, Li C, Liu M, Yang G, Huang X, Zhou F, Ma X. Wang X, et al. Among authors: huang s, huang x. Mol Ther. 2020 Feb 5;28(2):431-440. doi: 10.1016/j.ymthe.2019.11.022. Epub 2019 Nov 29. Mol Ther. 2020. PMID: 31843453 Free PMC article.

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