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SOCS Proteins Participate in the Regulation of Innate Immune Response Caused by Viruses.
Huang S, Liu K, Cheng A, Wang M, Cui M, Huang J, Zhu D, Chen S, Liu M, Zhao X, Wu Y, Yang Q, Zhang S, Ou X, Mao S, Gao Q, Yu Y, Tian B, Liu Y, Zhang L, Yin Z, Jing B, Chen X, Jia R. Huang S, et al. Among authors: huang j. Front Immunol. 2020 Sep 25;11:558341. doi: 10.3389/fimmu.2020.558341. eCollection 2020. Front Immunol. 2020. PMID: 33072096 Free PMC article. Review.
Duck Tembusu virus promotes the expression of suppressor of cytokine signaling 1 by downregulating miR-148a-5p to facilitate virus replication.
Huang S, Cheng A, Cui M, Pan Y, Wang M, Huang J, Zhu D, Chen S, Liu M, Zhao X, Wu Y, Yang Q, Zhang S, Ou X, Mao S, Yu Y, Tian B, Liu Y, Zhang L, Yin Z, Jing B, Chen X, Jia R. Huang S, et al. Among authors: huang j. Infect Genet Evol. 2020 Nov;85:104392. doi: 10.1016/j.meegid.2020.104392. Epub 2020 Jun 10. Infect Genet Evol. 2020. PMID: 32534026
The substitution at residue 218 of the NS5 protein methyltransferase domain of Tembusu virus impairs viral replication and translation and may triggers RIG-I-like receptor signaling.
Wu X, Pan Y, Huang J, Huang S, Wang M, Chen S, Liu M, Zhu D, Zhao X, Wu Y, Yang Q, Zhang S, Ou X, Zhang L, Liu Y, Yu Y, Gao Q, Mao S, Sun D, Tian B, Yin Z, Jing B, Cheng A, Jia R. Wu X, et al. Among authors: huang s, huang j. Poult Sci. 2022 Sep;101(9):102017. doi: 10.1016/j.psj.2022.102017. Epub 2022 Jun 20. Poult Sci. 2022. PMID: 35901648 Free PMC article.
Duck Tembusu Virus Inhibits Type I Interferon Production through the JOSD1-SOCS1-IRF7 Negative-Feedback Regulation Pathway.
Huang S, Huang J, Cui M, Wu X, Wang M, Zhu D, Chen S, Liu M, Zhao X, Wu Y, Yang Q, Zhang S, Ou X, Mao S, Gao Q, Yu Y, Tian B, Liu Y, Zhang L, Yin Z, Jing B, Chen X, Cheng A, Jia R. Huang S, et al. Among authors: huang j. J Virol. 2022 Sep 28;96(18):e0093022. doi: 10.1128/jvi.00930-22. Epub 2022 Sep 7. J Virol. 2022. PMID: 36069544 Free PMC article.
RNF123 Mediates Ubiquitination and Degradation of SOCS1 To Regulate Type I Interferon Production during Duck Tembusu Virus Infection.
Huang S, Cui M, Huang J, Wu Z, Cheng A, Wang M, Zhu D, Chen S, Liu M, Zhao X, Wu Y, Yang Q, Zhang S, Ou X, Mao S, Gao Q, Tian B, Sun D, Yin Z, Jing B, Jia R. Huang S, et al. Among authors: huang j. J Virol. 2023 Apr 27;97(4):e0009523. doi: 10.1128/jvi.00095-23. Epub 2023 Apr 4. J Virol. 2023. PMID: 37014223 Free PMC article.
A novel live attenuated duck Tembusu virus vaccine targeting N7 methyltransferase protects ducklings against pathogenic strains.
Wu X, Huang S, Wang M, Chen S, Liu M, Zhu D, Zhao X, Wu Y, Yang Q, Zhang S, Huang J, Ou X, Zhang L, Liu Y, Yu Y, Gao Q, Mao S, Sun D, Tian B, Yin Z, Jing B, Cheng A, Jia R. Wu X, et al. Among authors: huang s, huang j. Vet Res. 2023 Jun 12;54(1):47. doi: 10.1186/s13567-023-01170-0. Vet Res. 2023. PMID: 37308988 Free PMC article.
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