Huang R - Search Results

1

Drug-Induced Rhabdomyolysis Atlas (DIRA) for idiosyncratic adverse drug reaction management.

Wen Z, Liang Y, Hao Y, Delavan B, Huang R, Mikailov M, Tong W, Li M, Liu Z. Wen Z, et al. Among authors: huang r. Drug Discov Today. 2019 Jan;24(1):9-15. doi: 10.1016/j.drudis.2018.06.006. Epub 2018 Jun 11. Drug Discov Today. 2019. PMID: 29902520 Free PMC article. Review.

2

The Tox21 robotic platform for the assessment of environmental chemicals--from vision to reality.

Attene-Ramos MS, Miller N, Huang R, Michael S, Itkin M, Kavlock RJ, Austin CP, Shinn P, Simeonov A, Tice RR, Xia M. Attene-Ramos MS, et al. Among authors: huang r. Drug Discov Today. 2013 Aug;18(15-16):716-23. doi: 10.1016/j.drudis.2013.05.015. Epub 2013 May 31. Drug Discov Today. 2013. PMID: 23732176 Free PMC article. Review.

3

Profiling of the Tox21 10K compound library for agonists and antagonists of the estrogen receptor alpha signaling pathway.

Huang R, Sakamuru S, Martin MT, Reif DM, Judson RS, Houck KA, Casey W, Hsieh JH, Shockley KR, Ceger P, Fostel J, Witt KL, Tong W, Rotroff DM, Zhao T, Shinn P, Simeonov A, Dix DJ, Austin CP, Kavlock RJ, Tice RR, Xia M. Huang R, et al. Sci Rep. 2014 Jul 11;4:5664. doi: 10.1038/srep05664. Sci Rep. 2014. PMID: 25012808 Free PMC article.

4

Discovery of Transcriptional Targets Regulated by Nuclear Receptors Using a Probabilistic Graphical Model.

Lee M, Huang R, Tong W. Lee M, et al. Among authors: huang r. Toxicol Sci. 2016 Mar;150(1):64-73. doi: 10.1093/toxsci/kfv261. Epub 2015 Dec 7. Toxicol Sci. 2016. PMID: 26643261 Free PMC article.

5

Application of dynamic topic models to toxicogenomics data.

Lee M, Liu Z, Huang R, Tong W. Lee M, et al. Among authors: huang r. BMC Bioinformatics. 2016 Oct 6;17(Suppl 13):368. doi: 10.1186/s12859-016-1225-0. BMC Bioinformatics. 2016. PMID: 27766956 Free PMC article.

6

Integrating Drug's Mode of Action into Quantitative Structure-Activity Relationships for Improved Prediction of Drug-Induced Liver Injury.

Wu L, Liu Z, Auerbach S, Huang R, Chen M, McEuen K, Xu J, Fang H, Tong W. Wu L, et al. Among authors: huang r. J Chem Inf Model. 2017 Apr 24;57(4):1000-1006. doi: 10.1021/acs.jcim.6b00719. Epub 2017 Apr 10. J Chem Inf Model. 2017. PMID: 28350954 Free PMC article.

7

Computational drug repositioning for rare diseases in the era of precision medicine.

Delavan B, Roberts R, Huang R, Bao W, Tong W, Liu Z. Delavan B, et al. Among authors: huang r. Drug Discov Today. 2018 Feb;23(2):382-394. doi: 10.1016/j.drudis.2017.10.009. Epub 2017 Oct 18. Drug Discov Today. 2018. PMID: 29055182 Free article. Review.

8

Toxicogenomics: A 2020 Vision.

Liu Z, Huang R, Roberts R, Tong W. Liu Z, et al. Among authors: huang r. Trends Pharmacol Sci. 2019 Feb;40(2):92-103. doi: 10.1016/j.tips.2018.12.001. Epub 2018 Dec 26. Trends Pharmacol Sci. 2019. PMID: 30594306 Free PMC article. Review.

9

The NCATS Pharmaceutical Collection: a 10-year update.

Huang R, Zhu H, Shinn P, Ngan D, Ye L, Thakur A, Grewal G, Zhao T, Southall N, Hall MD, Simeonov A, Austin CP. Huang R, et al. Drug Discov Today. 2019 Dec;24(12):2341-2349. doi: 10.1016/j.drudis.2019.09.019. Epub 2019 Oct 1. Drug Discov Today. 2019. PMID: 31585169 Review.

10

Drug Repositioning for Noonan and LEOPARD Syndromes by Integrating Transcriptomics With a Structure-Based Approach.

Zhu L, Roberts R, Huang R, Zhao J, Xia M, Delavan B, Mikailov M, Tong W, Liu Z. Zhu L, et al. Among authors: huang r. Front Pharmacol. 2020 Jun 26;11:927. doi: 10.3389/fphar.2020.00927. eCollection 2020. Front Pharmacol. 2020. PMID: 32676024 Free PMC article.

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