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Potassium-regulated distal tubule WNK bodies are kidney-specific WNK1 dependent.
Boyd-Shiwarski CR, Shiwarski DJ, Roy A, Namboodiri HN, Nkashama LJ, Xie J, McClain KL, Marciszyn A, Kleyman TR, Tan RJ, Stolz DB, Puthenveedu MA, Huang CL, Subramanya AR. Boyd-Shiwarski CR, et al. Among authors: huang cl. Mol Biol Cell. 2018 Feb 15;29(4):499-509. doi: 10.1091/mbc.E17-08-0529. Epub 2017 Dec 13. Mol Biol Cell. 2018. PMID: 29237822 Free PMC article.
WNK4 kinase is a physiological intracellular chloride sensor.
Chen JC, Lo YF, Lin YW, Lin SH, Huang CL, Cheng CJ. Chen JC, et al. Among authors: huang cl. Proc Natl Acad Sci U S A. 2019 Mar 5;116(10):4502-4507. doi: 10.1073/pnas.1817220116. Epub 2019 Feb 14. Proc Natl Acad Sci U S A. 2019. PMID: 30765526 Free PMC article.
L-WNK1 is required for BK channel activation in intercalated cells.
Ray EC, Carrisoza-Gaytan R, Al-Bataineh M, Marciszyn AL, Nkashama LJ, Chen J, Winfrey A, Griffiths S, Lam TR, Flores D, Wu P, Wang W, Huang CL, Subramanya AR, Kleyman TR, Satlin LM. Ray EC, et al. Among authors: huang cl. Am J Physiol Renal Physiol. 2021 Aug 1;321(2):F245-F254. doi: 10.1152/ajprenal.00472.2020. Epub 2021 Jul 6. Am J Physiol Renal Physiol. 2021. PMID: 34229479 Free PMC article.
Domains of WNK1 kinase in the regulation of ROMK1.
Wang HR, Liu Z, Huang CL. Wang HR, et al. Among authors: huang cl. Am J Physiol Renal Physiol. 2008 Aug;295(2):F438-45. doi: 10.1152/ajprenal.90287.2008. Epub 2008 Jun 11. Am J Physiol Renal Physiol. 2008. PMID: 18550644 Free PMC article.
1,573 results