Hu J - Search Results

1

Inhibition of Autophagy by a Small Molecule through Covalent Modification of the LC3 Protein.

Fan S, Yue L, Wan W, Zhang Y, Zhang B, Otomo C, Li Q, Lin T, Hu J, Xu P, Zhu M, Tao H, Chen Z, Li L, Ding H, Yao Z, Lu J, Wen Y, Zhang N, Tan M, Chen K, Xie Y, Otomo T, Zhou B, Jiang H, Dang Y, Luo C. Fan S, et al. Among authors: hu j. Angew Chem Int Ed Engl. 2021 Dec 6;60(50):26105-26114. doi: 10.1002/anie.202109464. Epub 2021 Nov 5. Angew Chem Int Ed Engl. 2021. PMID: 34590387 Free PMC article.

2

Identifying novel selective non-nucleoside DNA methyltransferase 1 inhibitors through docking-based virtual screening.

Chen S, Wang Y, Zhou W, Li S, Peng J, Shi Z, Hu J, Liu YC, Ding H, Lin Y, Li L, Cheng S, Liu J, Lu T, Jiang H, Liu B, Zheng M, Luo C. Chen S, et al. Among authors: hu j. J Med Chem. 2014 Nov 13;57(21):9028-41. doi: 10.1021/jm501134e. Epub 2014 Nov 4. J Med Chem. 2014. PMID: 25333769

3

Identification of Novel Disruptor of Telomeric Silencing 1-like (DOT1L) Inhibitors through Structure-Based Virtual Screening and Biological Assays.

Chen S, Li L, Chen Y, Hu J, Liu J, Liu YC, Liu R, Zhang Y, Meng F, Zhu K, Lu J, Zheng M, Chen K, Zhang J, Jiang H, Yao Z, Luo C. Chen S, et al. Among authors: hu j. J Chem Inf Model. 2016 Mar 28;56(3):527-34. doi: 10.1021/acs.jcim.5b00738. Epub 2016 Mar 4. J Chem Inf Model. 2016. PMID: 26914852

4

Identification of novel EZH2 inhibitors through pharmacophore-based virtual screening and biological assays.

Wu Y, Hu J, Ding H, Chen L, Zhang Y, Liu R, Xu P, Du D, Lu W, Liu J, Liu Y, Liu YC, Lu J, Zhang J, Yao Z, Luo C. Wu Y, et al. Among authors: hu j. Bioorg Med Chem Lett. 2016 Aug 1;26(15):3813-7. doi: 10.1016/j.bmcl.2016.05.018. Epub 2016 May 30. Bioorg Med Chem Lett. 2016. PMID: 27289323

5

Conformation and dynamics of the C-terminal region in human phosphoglycerate mutase 1.

Liu SE, Hu JC, Zhang H, Xu P, Wan W, Zheng MY, Yu KQ, Ding H, Jiang HL, Zhou L, Luo C. Liu SE, et al. Acta Pharmacol Sin. 2017 Dec;38(12):1673-1682. doi: 10.1038/aps.2017.37. Epub 2017 Jul 27. Acta Pharmacol Sin. 2017. PMID: 28748916 Free PMC article.

6

Development of a high-throughput fluorescence polarization assay for the discovery of EZH2-EED interaction inhibitors.

Zhu MR, Du DH, Hu JC, Li LC, Liu JQ, Ding H, Kong XQ, Jiang HL, Chen KX, Luo C. Zhu MR, et al. Acta Pharmacol Sin. 2018 Feb;39(2):302-310. doi: 10.1038/aps.2017.59. Epub 2017 Aug 31. Acta Pharmacol Sin. 2018. PMID: 28858300 Free PMC article.

7

The Human Knockout Gene CLYBL Connects Itaconate to Vitamin B₁₂.

Shen H, Campanello GC, Flicker D, Grabarek Z, Hu J, Luo C, Banerjee R, Mootha VK. Shen H, et al. Among authors: hu j. Cell. 2017 Nov 2;171(4):771-782.e11. doi: 10.1016/j.cell.2017.09.051. Epub 2017 Oct 19. Cell. 2017. PMID: 29056341 Free PMC article.

8

Interaction assessments of the first S-adenosylmethionine competitive inhibitor and the essential interacting partner methylosome protein 50 with protein arginine methyltransferase 5 by combined computational methods.

Zhu K, Jiang CS, Hu J, Liu X, Yan X, Tao H, Luo C, Zhang H. Zhu K, et al. Among authors: hu j. Biochem Biophys Res Commun. 2018 Jan 1;495(1):721-727. doi: 10.1016/j.bbrc.2017.11.089. Epub 2017 Nov 14. Biochem Biophys Res Commun. 2018. PMID: 29154828

9

Identification and Characterizations of Novel, Selective Histone Methyltransferase SET7 Inhibitors by Scaffold Hopping- and 2D-Molecular Fingerprint-Based Similarity Search.

Ding H, Lu WC, Hu JC, Liu YC, Zhang CH, Lian FL, Zhang NX, Meng FW, Luo C, Chen KX. Ding H, et al. Molecules. 2018 Mar 2;23(3):567. doi: 10.3390/molecules23030567. Molecules. 2018. PMID: 29498708 Free PMC article.

10

Deciphering the role of dimer interface in intrinsic dynamics and allosteric pathways underlying the functional transformation of DNMT3A.

Liang Z, Hu J, Yan W, Jiang H, Hu G, Luo C. Liang Z, et al. Among authors: hu g, hu j. Biochim Biophys Acta Gen Subj. 2018 Jul;1862(7):1667-1679. doi: 10.1016/j.bbagen.2018.04.015. Epub 2018 Apr 16. Biochim Biophys Acta Gen Subj. 2018. PMID: 29674125

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