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Altered host protease determinants for SARS-CoV-2 Omicron.
Chan JF, Huang X, Hu B, Chai Y, Shi H, Zhu T, Yuen TT, Liu Y, Liu H, Shi J, Wen L, Shuai H, Hou Y, Yoon C, Cai JP, Zhang AJ, Zhou J, Yin F, Yuan S, Zhang BZ, Brindley MA, Shi ZL, Yuen KY, Chu H. Chan JF, et al. Among authors: hu b. Sci Adv. 2023 Jan 20;9(3):eadd3867. doi: 10.1126/sciadv.add3867. Epub 2023 Jan 20. Sci Adv. 2023. PMID: 36662861 Free PMC article.
Comparative Replication and Immune Activation Profiles of SARS-CoV-2 and SARS-CoV in Human Lungs: An Ex Vivo Study With Implications for the Pathogenesis of COVID-19.
Chu H, Chan JF, Wang Y, Yuen TT, Chai Y, Hou Y, Shuai H, Yang D, Hu B, Huang X, Zhang X, Cai JP, Zhou J, Yuan S, Kok KH, To KK, Chan IH, Zhang AJ, Sit KY, Au WK, Yuen KY. Chu H, et al. Among authors: hu b. Clin Infect Dis. 2020 Sep 12;71(6):1400-1409. doi: 10.1093/cid/ciaa410. Clin Infect Dis. 2020. PMID: 32270184 Free PMC article.
Comparative tropism, replication kinetics, and cell damage profiling of SARS-CoV-2 and SARS-CoV with implications for clinical manifestations, transmissibility, and laboratory studies of COVID-19: an observational study.
Chu H, Chan JF, Yuen TT, Shuai H, Yuan S, Wang Y, Hu B, Yip CC, Tsang JO, Huang X, Chai Y, Yang D, Hou Y, Chik KK, Zhang X, Fung AY, Tsoi HW, Cai JP, Chan WM, Ip JD, Chu AW, Zhou J, Lung DC, Kok KH, To KK, Tsang OT, Chan KH, Yuen KY. Chu H, et al. Among authors: hu b. Lancet Microbe. 2020 May;1(1):e14-e23. doi: 10.1016/S2666-5247(20)30004-5. Epub 2020 Apr 21. Lancet Microbe. 2020. PMID: 32835326 Free PMC article.
Bat mammalian orthoreoviruses cause severe pneumonia in mice.
Jiang RD, Li B, Liu XL, Liu MQ, Chen J, Luo DS, Hu BJ, Zhang W, Li SY, Yang XL, Shi ZL. Jiang RD, et al. Among authors: hu bj. Virology. 2020 Dec;551:84-92. doi: 10.1016/j.virol.2020.05.014. Epub 2020 Jun 22. Virology. 2020. PMID: 32859395 Free PMC article.
SARS-CoV-2 Induces a More Robust Innate Immune Response and Replicates Less Efficiently Than SARS-CoV in the Human Intestines: An Ex Vivo Study With Implications on Pathogenesis of COVID-19.
Chu H, Chan JF, Wang Y, Yuen TT, Chai Y, Shuai H, Yang D, Hu B, Huang X, Zhang X, Hou Y, Cai JP, Zhang AJ, Zhou J, Yuan S, To KK, Hung IF, Cheung TT, Ng AT, Hau-Yee Chan I, Wong IY, Law SY, Foo DC, Leung WK, Yuen KY. Chu H, et al. Among authors: hu b. Cell Mol Gastroenterol Hepatol. 2021;11(3):771-781. doi: 10.1016/j.jcmgh.2020.09.017. Epub 2020 Oct 1. Cell Mol Gastroenterol Hepatol. 2021. PMID: 33010495 Free PMC article.
Host and viral determinants for efficient SARS-CoV-2 infection of the human lung.
Chu H, Hu B, Huang X, Chai Y, Zhou D, Wang Y, Shuai H, Yang D, Hou Y, Zhang X, Yuen TT, Cai JP, Zhang AJ, Zhou J, Yuan S, To KK, Chan IH, Sit KY, Foo DC, Wong IY, Ng AT, Cheung TT, Law SY, Au WK, Brindley MA, Chen Z, Kok KH, Chan JF, Yuen KY. Chu H, et al. Among authors: hu b. Nat Commun. 2021 Jan 8;12(1):134. doi: 10.1038/s41467-020-20457-w. Nat Commun. 2021. PMID: 33420022 Free PMC article.
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