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Targeting conserved N-glycosylation blocks SARS-CoV-2 variant infection in vitro.
Huang HC, Lai YJ, Liao CC, Yang WF, Huang KB, Lee IJ, Chou WC, Wang SH, Wang LH, Hsu JM, Sun CP, Kuo CT, Wang J, Hsiao TC, Yang PJ, Lee TA, Huang W, Li FA, Shen CY, Lin YL, Tao MH, Li CW. Huang HC, et al. Among authors: hsu jm. EBioMedicine. 2021 Dec;74:103712. doi: 10.1016/j.ebiom.2021.103712. Epub 2021 Nov 25. EBioMedicine. 2021. PMID: 34839261 Free PMC article.
AKT1 Inhibits Epithelial-to-Mesenchymal Transition in Breast Cancer through Phosphorylation-Dependent Twist1 Degradation.
Li CW, Xia W, Lim SO, Hsu JL, Huo L, Wu Y, Li LY, Lai CC, Chang SS, Hsu YH, Sun HL, Kim J, Yamaguchi H, Lee DF, Wang H, Wang Y, Chou CK, Hsu JM, Lai YJ, LaBaff AM, Ding Q, Ko HW, Tsai FJ, Tsai CH, Hortobagyi GN, Hung MC. Li CW, et al. Among authors: hsu yh, hsu jl, hsu jm. Cancer Res. 2016 Mar 15;76(6):1451-62. doi: 10.1158/0008-5472.CAN-15-1941. Epub 2016 Jan 12. Cancer Res. 2016. PMID: 26759241 Free PMC article.
Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity.
Li CW, Lim SO, Xia W, Lee HH, Chan LC, Kuo CW, Khoo KH, Chang SS, Cha JH, Kim T, Hsu JL, Wu Y, Hsu JM, Yamaguchi H, Ding Q, Wang Y, Yao J, Lee CC, Wu HJ, Sahin AA, Allison JP, Yu D, Hortobagyi GN, Hung MC. Li CW, et al. Among authors: hsu jl, hsu jm. Nat Commun. 2016 Aug 30;7:12632. doi: 10.1038/ncomms12632. Nat Commun. 2016. PMID: 27572267 Free PMC article.
Eradication of Triple-Negative Breast Cancer Cells by Targeting Glycosylated PD-L1.
Li CW, Lim SO, Chung EM, Kim YS, Park AH, Yao J, Cha JH, Xia W, Chan LC, Kim T, Chang SS, Lee HH, Chou CK, Liu YL, Yeh HC, Perillo EP, Dunn AK, Kuo CW, Khoo KH, Hsu JL, Wu Y, Hsu JM, Yamaguchi H, Huang TH, Sahin AA, Hortobagyi GN, Yoo SS, Hung MC. Li CW, et al. Among authors: hsu jl, hsu jm. Cancer Cell. 2018 Feb 12;33(2):187-201.e10. doi: 10.1016/j.ccell.2018.01.009. Cancer Cell. 2018. PMID: 29438695 Free PMC article.
STT3-dependent PD-L1 accumulation on cancer stem cells promotes immune evasion.
Hsu JM, Xia W, Hsu YH, Chan LC, Yu WH, Cha JH, Chen CT, Liao HW, Kuo CW, Khoo KH, Hsu JL, Li CW, Lim SO, Chang SS, Chen YC, Ren GX, Hung MC. Hsu JM, et al. Among authors: hsu yh, hsu jl. Nat Commun. 2018 May 15;9(1):1908. doi: 10.1038/s41467-018-04313-6. Nat Commun. 2018. PMID: 29765039 Free PMC article.
Palmitoylation stabilizes PD-L1 to promote breast tumor growth.
Yang Y, Hsu JM, Sun L, Chan LC, Li CW, Hsu JL, Wei Y, Xia W, Hou J, Qiu Y, Hung MC. Yang Y, et al. Among authors: hsu jl, hsu jm. Cell Res. 2019 Jan;29(1):83-86. doi: 10.1038/s41422-018-0124-5. Epub 2018 Dec 4. Cell Res. 2019. PMID: 30514902 Free PMC article. No abstract available.
MET Inhibitors Promote Liver Tumor Evasion of the Immune Response by Stabilizing PDL1.
Li H, Li CW, Li X, Ding Q, Guo L, Liu S, Liu C, Lai CC, Hsu JM, Dong Q, Xia W, Hsu JL, Yamaguchi H, Du Y, Lai YJ, Sun X, Koller PB, Ye Q, Hung MC. Li H, et al. Among authors: hsu jl, hsu jm. Gastroenterology. 2019 May;156(6):1849-1861.e13. doi: 10.1053/j.gastro.2019.01.252. Epub 2019 Jan 31. Gastroenterology. 2019. PMID: 30711629 Free PMC article.
228 results