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Omecamtiv mecarbil does not prolong QTc intervals at therapeutic concentrations.
Trivedi A, Hsu CP, Jafarinasabian P, Terminello B, Zhang H, Flach S, Israel S, Brooks A, Xue H, Darpo B, Abbasi S, Dutta S, Lee E. Trivedi A, et al. Among authors: hsu cp. Br J Clin Pharmacol. 2022 Jan;88(1):187-198. doi: 10.1111/bcp.14939. Epub 2021 Jul 16. Br J Clin Pharmacol. 2022. PMID: 34131942 Free article. Clinical Trial.
A Phase 1, Randomized, Double-Blind, Single-Dose, Placebo-Controlled Safety, Tolerability, And Pharmacokinetic/Pharmacodynamic Study Of Evolocumab In Healthy Chinese Subjects.
Liu C, Lu H, Yuan F, Chen WL, Xu HR, Li H, Hsu CP, Egbuna O, Wu J, Dias C, Abosaleem B, Rana J, Monsalvo ML, Li XN, Yu Z. Liu C, et al. Among authors: hsu cp. Clin Pharmacol. 2019 Oct 23;11:145-153. doi: 10.2147/CPAA.S208033. eCollection 2019. Clin Pharmacol. 2019. PMID: 31695519 Free PMC article.
Translational pharmacokinetic-pharmacodynamic analysis in the pharmaceutical industry: an IQ Consortium PK-PD Discussion Group perspective.
Wong H, Bohnert T, Damian-Iordache V, Gibson C, Hsu CP, Krishnatry AS, Liederer BM, Lin J, Lu Q, Mettetal JT, Mudra DR, Nijsen MJMA, Schroeder P, Schuck E, Suryawanshi S, Trapa P, Tsai A, Wang H, Wu F. Wong H, et al. Among authors: hsu cp. Drug Discov Today. 2017 Oct;22(10):1447-1459. doi: 10.1016/j.drudis.2017.04.015. Epub 2017 May 2. Drug Discov Today. 2017. PMID: 28476536 Review.
515 results