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Deficiency in coatomer complex I causes aberrant activation of STING signalling.
Nat Commun. 2022 Apr 28;13(1):2321. doi: 10.1038/s41467-022-29946-6.
Nat Commun. 2022.
PMID: 35484149
Free PMC article.
Organellar homeostasis and innate immune sensing.
Harapas CR, Idiiatullina E, Al-Azab M, Hrovat-Schaale K, Reygaerts T, Steiner A, Laohamonthonkul P, Davidson S, Yu CH, Booty L, Masters SL.
Harapas CR, et al. Among authors: hrovat schaale k.
Nat Rev Immunol. 2022 Sep;22(9):535-549. doi: 10.1038/s41577-022-00682-8. Epub 2022 Feb 23.
Nat Rev Immunol. 2022.
PMID: 35197578
Review.
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Protein kinase R is an innate immune sensor of proteotoxic stress via accumulation of cytoplasmic IL-24.
Davidson S, Yu CH, Steiner A, Ebstein F, Baker PJ, Jarur-Chamy V, Hrovat Schaale K, Laohamonthonkul P, Kong K, Calleja DJ, Harapas CR, Balka KR, Mitchell J, Jackson JT, Geoghegan ND, Moghaddas F, Rogers KL, Mayer-Barber KD, De Jesus AA, De Nardo D, Kile BT, Sadler AJ, Poli MC, Krüger E, Goldbach Mansky R, Masters SL.
Davidson S, et al. Among authors: hrovat schaale k.
Sci Immunol. 2022 Feb 11;7(68):eabi6763. doi: 10.1126/sciimmunol.abi6763. Epub 2022 Feb 11.
Sci Immunol. 2022.
PMID: 35148201
Free PMC article.
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NLRP1 variant M1184V decreases inflammasome activation in the context of DPP9 inhibition and asthma severity.
Moecking J, Laohamonthonkul P, Chalker K, White MJ, Harapas CR, Yu CH, Davidson S, Hrovat-Schaale K, Hu D, Eng C, Huntsman S, Calleja DJ, Horvat JC, Hansbro PM, O'Donoghue RJJ, Ting JP, Burchard EG, Geyer M, Gerlic M, Masters SL.
Moecking J, et al. Among authors: hrovat schaale k.
J Allergy Clin Immunol. 2021 Jun;147(6):2134-2145.e20. doi: 10.1016/j.jaci.2020.12.636. Epub 2020 Dec 27.
J Allergy Clin Immunol. 2021.
PMID: 33378691
Free PMC article.
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Pyrin variant E148Q potentiates inflammasome activation and the effect of pathogenic mutations in cis.
Reygaerts T, Laohamonthonkul P, Hrovat-Schaale K, Moghaddas F, Baker PJ, Gray PE, Masters SL.
Reygaerts T, et al. Among authors: hrovat schaale k.
Rheumatology (Oxford). 2024 Mar 1;63(3):882-890. doi: 10.1093/rheumatology/kead376.
Rheumatology (Oxford). 2024.
PMID: 37481715
Free PMC article.
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