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Hypothermia is not therapeutic in a neonatal piglet model of inflammation-sensitized hypoxia-ischemia.
Martinello KA, Meehan C, Avdic-Belltheus A, Lingam I, Mutshiya T, Yang Q, Akin MA, Price D, Sokolska M, Bainbridge A, Hristova M, Tachtsidis I, Tann CJ, Peebles D, Hagberg H, Wolfs TGAM, Klein N, Kramer BW, Fleiss B, Gressens P, Golay X, Robertson NJ. Martinello KA, et al. Among authors: hristova m. Pediatr Res. 2022 May;91(6):1416-1427. doi: 10.1038/s41390-021-01584-6. Epub 2021 May 28. Pediatr Res. 2022. PMID: 34050269 Free PMC article. Clinical Trial.
TNF gene cluster deletion abolishes lipopolysaccharide-mediated sensitization of the neonatal brain to hypoxic ischemic insult.
Kendall GS, Hristova M, Horn S, Dafou D, Acosta-Saltos A, Almolda B, Zbarsky V, Rumajogee P, Heuer H, Castellano B, Pfeffer K, Nedospasov SA, Peebles DM, Raivich G. Kendall GS, et al. Among authors: hristova m. Lab Invest. 2011 Mar;91(3):328-41. doi: 10.1038/labinvest.2010.192. Epub 2010 Dec 6. Lab Invest. 2011. PMID: 21135813 Free article.
Melatonin augments hypothermic neuroprotection in a perinatal asphyxia model.
Robertson NJ, Faulkner S, Fleiss B, Bainbridge A, Andorka C, Price D, Powell E, Lecky-Thompson L, Thei L, Chandrasekaran M, Hristova M, Cady EB, Gressens P, Golay X, Raivich G. Robertson NJ, et al. Among authors: hristova m. Brain. 2013 Jan;136(Pt 1):90-105. doi: 10.1093/brain/aws285. Epub 2012 Nov 26. Brain. 2013. PMID: 23183236
Brain cell death is reduced with cooling by 3.5°C to 5°C but increased with cooling by 8.5°C in a piglet asphyxia model.
Alonso-Alconada D, Broad KD, Bainbridge A, Chandrasekaran M, Faulkner SD, Kerenyi Á, Hassell J, Rocha-Ferreira E, Hristova M, Fleiss B, Bennett K, Kelen D, Cady E, Gressens P, Golay X, Robertson NJ. Alonso-Alconada D, et al. Among authors: hristova m. Stroke. 2015 Jan;46(1):275-8. doi: 10.1161/STROKEAHA.114.007330. Epub 2014 Nov 25. Stroke. 2015. PMID: 25424475 Free PMC article.
Immediate remote ischemic postconditioning after hypoxia ischemia in piglets protects cerebral white matter but not grey matter.
Ezzati M, Bainbridge A, Broad KD, Kawano G, Oliver-Taylor A, Rocha-Ferreira E, Alonso-Alconada D, Fierens I, Rostami J, Jane Hassell K, Tachtsidis I, Gressens P, Hristova M, Bennett K, Lebon S, Fleiss B, Yellon D, Hausenloy DJ, Golay X, Robertson NJ. Ezzati M, et al. Among authors: hristova m. J Cereb Blood Flow Metab. 2016 Aug;36(8):1396-411. doi: 10.1177/0271678X15608862. Epub 2015 Oct 8. J Cereb Blood Flow Metab. 2016. PMID: 26661194 Free PMC article.
150 results