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The intervertebral disc contains intrinsic circadian clocks that are regulated by age and cytokines and linked to degeneration.
Dudek M, Yang N, Ruckshanthi JP, Williams J, Borysiewicz E, Wang P, Adamson A, Li J, Bateman JF, White MR, Boot-Handford RP, Hoyland JA, Meng QJ. Dudek M, et al. Among authors: hoyland ja. Ann Rheum Dis. 2017 Mar;76(3):576-584. doi: 10.1136/annrheumdis-2016-209428. Epub 2016 Aug 3. Ann Rheum Dis. 2017. PMID: 27489225 Free PMC article.
Publication trends in spine research from 2007 to 2016: Comparison of the Orthopaedic Research Society Spine Section and the International Society for the Study of the Lumbar Spine.
Martin JT, Gullbrand SE, Fields AJ, Purmessur D, Diwan AD, Oxland TR, Chiba K, Guilak F, Hoyland JA, Iatridis JC. Martin JT, et al. Among authors: hoyland ja. JOR Spine. 2018 Mar;1(1):e1006. doi: 10.1002/jsp2.1006. Epub 2018 Mar 23. JOR Spine. 2018. PMID: 29770804 Free PMC article.
Quantitative live imaging of Venus::BMAL1 in a mouse model reveals complex dynamics of the master circadian clock regulator.
Yang N, Smyllie NJ, Morris H, Gonçalves CF, Dudek M, Pathiranage DRJ, Chesham JE, Adamson A, Spiller DG, Zindy E, Bagnall J, Humphreys N, Hoyland J, Loudon ASI, Hastings MH, Meng QJ. Yang N, et al. PLoS Genet. 2020 Apr 30;16(4):e1008729. doi: 10.1371/journal.pgen.1008729. eCollection 2020 Apr. PLoS Genet. 2020. PMID: 32352975 Free PMC article.
Circadian time series proteomics reveals daily dynamics in cartilage physiology.
Dudek M, Angelucci C, Pathiranage D, Wang P, Mallikarjun V, Lawless C, Swift J, Kadler KE, Boot-Handford RP, Hoyland JA, Lamande SR, Bateman JF, Meng QJ. Dudek M, et al. Among authors: hoyland ja. Osteoarthritis Cartilage. 2021 May;29(5):739-749. doi: 10.1016/j.joca.2021.02.008. Epub 2021 Feb 19. Osteoarthritis Cartilage. 2021. PMID: 33610821 Free PMC article.
Restoring the dampened expression of the core clock molecule BMAL1 protects against compression-induced intervertebral disc degeneration.
Wang D, Peng P, Dudek M, Hu X, Xu X, Shang Q, Wang D, Jia H, Wang H, Gao B, Zheng C, Mao J, Gao C, He X, Cheng P, Wang H, Zheng J, Hoyland JA, Meng QJ, Luo Z, Yang L. Wang D, et al. Among authors: hoyland ja. Bone Res. 2022 Feb 25;10(1):20. doi: 10.1038/s41413-022-00187-z. Bone Res. 2022. PMID: 35217644 Free PMC article.
Harmonization and standardization of nucleus pulposus cell extraction and culture methods.
Basatvat S, Bach FC, Barcellona MN, Binch AL, Buckley CT, Bueno B, Chahine NO, Chee A, Creemers LB, Dudli S, Fearing B, Ferguson SJ, Gansau J, Gantenbein B, Gawri R, Glaeser JD, Grad S, Guerrero J, Haglund L, Hernandez PA, Hoyland JA, Huang C, Iatridis JC, Illien-Junger S, Jing L, Kraus P, Laagland LT, Lang G, Leung V, Li Z, Lufkin T, van Maanen JC, McDonnell EE, Panebianco CJ, Presciutti SM, Rao S, Richardson SM, Romereim S, Schmitz TC, Schol J, Setton L, Sheyn D, Snuggs JW, Sun Y, Tan X, Tryfonidou MA, Vo N, Wang D, Williams B, Williams R, Yoon ST, Le Maitre CL. Basatvat S, et al. Among authors: hoyland ja. JOR Spine. 2023 Jan 10;6(1):e1238. doi: 10.1002/jsp2.1238. eCollection 2023 Mar. JOR Spine. 2023. PMID: 36994456 Free PMC article.
213 results