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Page 1
Longitudinal Multi-omics Analyses Identify Responses of Megakaryocytes, Erythroid Cells, and Plasmablasts as Hallmarks of Severe COVID-19.
Bernardes JP, Mishra N, Tran F, Bahmer T, Best L, Blase JI, Bordoni D, Franzenburg J, Geisen U, Josephs-Spaulding J, Köhler P, Künstner A, Rosati E, Aschenbrenner AC, Bacher P, Baran N, Boysen T, Brandt B, Bruse N, Dörr J, Dräger A, Elke G, Ellinghaus D, Fischer J, Forster M, Franke A, Franzenburg S, Frey N, Friedrichs A, Fuß J, Glück A, Hamm J, Hinrichsen F, Hoeppner MP, Imm S, Junker R, Kaiser S, Kan YH, Knoll R, Lange C, Laue G, Lier C, Lindner M, Marinos G, Markewitz R, Nattermann J, Noth R, Pickkers P, Rabe KF, Renz A, Röcken C, Rupp J, Schaffarzyk A, Scheffold A, Schulte-Schrepping J, Schunk D, Skowasch D, Ulas T, Wandinger KP, Wittig M, Zimmermann J, Busch H, Hoyer BF, Kaleta C, Heyckendorf J, Kox M, Rybniker J, Schreiber S, Schultze JL, Rosenstiel P; HCA Lung Biological Network; Deutsche COVID-19 Omics Initiative (DeCOI). Bernardes JP, et al. Among authors: hoyer bf. Immunity. 2020 Dec 15;53(6):1296-1314.e9. doi: 10.1016/j.immuni.2020.11.017. Epub 2020 Nov 26. Immunity. 2020. PMID: 33296687 Free PMC article.
Immunogenicity and safety of anti-SARS-CoV-2 mRNA vaccines in patients with chronic inflammatory conditions and immunosuppressive therapy in a monocentric cohort.
Geisen UM, Berner DK, Tran F, Sümbül M, Vullriede L, Ciripoi M, Reid HM, Schaffarzyk A, Longardt AC, Franzenburg J, Hoff P, Schirmer JH, Zeuner R, Friedrichs A, Steinbach A, Knies C, Markewitz RD, Morrison PJ, Gerdes S, Schreiber S, Hoyer BF. Geisen UM, et al. Among authors: hoyer bf. Ann Rheum Dis. 2021 Oct;80(10):1306-1311. doi: 10.1136/annrheumdis-2021-220272. Epub 2021 Mar 24. Ann Rheum Dis. 2021. PMID: 33762264 Free PMC article.
Humoral protection to SARS-CoV2 declines faster in patients on TNF alpha blocking therapies.
Geisen UM, Sümbül M, Tran F, Berner DK, Reid HM, Vullriede L, Ciripoi M, Longardt AC, Hoff P, Morrison PJ, Schneider VE, Zeuner R, Schirmer JH, Steinbach A, Nikolaus S, Gerdes S, Schreiber S, Bacher P, Hoyer BF. Geisen UM, et al. Among authors: hoyer bf. RMD Open. 2021 Dec;7(3):e002008. doi: 10.1136/rmdopen-2021-002008. RMD Open. 2021. PMID: 34880128 Free PMC article.
The long term vaccine-induced anti-SARS-CoV-2 immune response is impaired in quantity and quality under TNFα blockade.
Geisen UM, Rose R, Neumann F, Ciripoi M, Vullriede L, Reid HM, Berner DK, Bertoglio F, Hoff P, Hust M, Longardt AC, Lorentz T, Martini GR, Saggau C, Schirmer JH, Schubert M, Sümbül M, Tran F, Voß M, Zeuner R, Morrison PJ, Bacher P, Fickenscher H, Gerdes S, Peipp M, Schreiber S, Krumbholz A, Hoyer BF. Geisen UM, et al. Among authors: hoyer bf. J Med Virol. 2022 Dec;94(12):5780-5789. doi: 10.1002/jmv.28063. Epub 2022 Aug 19. J Med Virol. 2022. PMID: 35945627 Free PMC article.
The pre-exposure SARS-CoV-2-specific T cell repertoire determines the quality of the immune response to vaccination.
Saggau C, Martini GR, Rosati E, Meise S, Messner B, Kamps AK, Bekel N, Gigla J, Rose R, Voß M, Geisen UM, Reid HM, Sümbül M, Tran F, Berner DK, Khodamoradi Y, Vehreschild MJGT, Cornely O, Koehler P, Krumbholz A, Fickenscher H, Kreuzer O, Schreiber C, Franke A, Schreiber S, Hoyer B, Scheffold A, Bacher P. Saggau C, et al. Immunity. 2022 Oct 11;55(10):1924-1939.e5. doi: 10.1016/j.immuni.2022.08.003. Epub 2022 Aug 12. Immunity. 2022. PMID: 35985324 Free PMC article.
Increased protease-activated receptor 1 autoantibodies are associated with severe COVID-19.
Tran F, Harris DMM, Scharmacher A, Graßhoff H, Sterner K, Schinke S, Käding N, Humrich JY, Cabral-Marques O, Bernardes JP, Mishra N, Bahmer T, Franzenburg J, Hoyer BF, Glück A, Guggeis M, Ossysek A, Küller A, Frank D, Lange C, Rupp J, Heyckendorf J, Gaede KI, Amital H, Rosenstiel P, Shoenfeld Y, Halpert G, Rosenberg AZ, Schulze-Forster K, Heidecke H, Riemekasten G, Schreiber S. Tran F, et al. Among authors: hoyer bf. ERJ Open Res. 2022 Dec 27;8(4):00379-2022. doi: 10.1183/23120541.00379-2022. eCollection 2022 Oct. ERJ Open Res. 2022. PMID: 36575710 Free PMC article.
Memory B and memory plasma cells.
Yoshida T, Mei H, Dörner T, Hiepe F, Radbruch A, Fillatreau S, Hoyer BF. Yoshida T, et al. Among authors: hoyer bf. Immunol Rev. 2010 Sep;237(1):117-39. doi: 10.1111/j.1600-065X.2010.00938.x. Immunol Rev. 2010. PMID: 20727033 Review.
108 results