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Aging-regulated anti-apoptotic long non-coding RNA Sarrah augments recovery from acute myocardial infarction.
Trembinski DJ, Bink DI, Theodorou K, Sommer J, Fischer A, van Bergen A, Kuo CC, Costa IG, Schürmann C, Leisegang MS, Brandes RP, Alekseeva T, Brill B, Wietelmann A, Johnson CN, Spring-Connell A, Kaulich M, Werfel S, Engelhardt S, Hirt MN, Yorgan K, Eschenhagen T, Kirchhof L, Hofmann P, Jaé N, Wittig I, Hamdani N, Bischof C, Krishnan J, Houtkooper RH, Dimmeler S, Boon RA. Trembinski DJ, et al. Among authors: houtkooper rh. Nat Commun. 2020 Apr 27;11(1):2039. doi: 10.1038/s41467-020-15995-2. Nat Commun. 2020. PMID: 32341350 Free PMC article.
Long noncoding RNAs in cardiometabolic disorders.
Juni RP, 't Hart KC, Houtkooper RH, Boon RA. Juni RP, et al. Among authors: houtkooper rh. FEBS Lett. 2022 Jun;596(11):1367-1387. doi: 10.1002/1873-3468.14370. Epub 2022 May 26. FEBS Lett. 2022. PMID: 35531641 Free article. Review.
The mouse metallomic landscape of aging and metabolism.
Morel JD, Sauzéat L, Goeminne LJE, Jha P, Williams E, Houtkooper RH, Aebersold R, Auwerx J, Balter V. Morel JD, et al. Among authors: houtkooper rh. Nat Commun. 2022 Feb 1;13(1):607. doi: 10.1038/s41467-022-28060-x. Nat Commun. 2022. PMID: 35105883 Free PMC article.
Peripheral modulation of antidepressant targets MAO-B and GABAAR by harmol induces mitohormesis and delays aging in preclinical models.
Costa-Machado LF, Garcia-Dominguez E, McIntyre RL, Lopez-Aceituno JL, Ballesteros-Gonzalez Á, Tapia-Gonzalez A, Fabregat-Safont D, Eisenberg T, Gomez J, Plaza A, Sierra-Ramirez A, Perez M, Villanueva-Bermejo D, Fornari T, Loza MI, Herradon G, Hofer SJ, Magnes C, Madeo F, Duerr JS, Pozo OJ, Galindo MI, Del Pino I, Houtkooper RH, Megias D, Viña J, Gomez-Cabrera MC, Fernandez-Marcos PJ. Costa-Machado LF, et al. Among authors: houtkooper rh. Nat Commun. 2023 May 15;14(1):2779. doi: 10.1038/s41467-023-38410-y. Nat Commun. 2023. PMID: 37188705 Free PMC article.
HDAC1/2 inhibitor therapy improves multiple organ systems in aged mice.
Tammaro A, Daniels EG, Hu IM, 't Hart KC, Reid K, Juni RP, Butter LM, Vasam G, Kamble R, Jongejan A, Aviv RI, Roelofs JJTH, Aronica E, Boon RA, Menzies KJ, Houtkooper RH, Janssens GE. Tammaro A, et al. Among authors: houtkooper rh. iScience. 2023 Dec 12;27(1):108681. doi: 10.1016/j.isci.2023.108681. eCollection 2024 Jan 19. iScience. 2023. PMID: 38269100 Free PMC article.
Enzyme engineering to fight mitochondrial diseases.
Zapata-Pérez R, Houtkooper RH. Zapata-Pérez R, et al. Among authors: houtkooper rh. Nat Metab. 2020 Mar;2(3):215-216. doi: 10.1038/s42255-020-0177-x. Nat Metab. 2020. PMID: 32694771 No abstract available.
Effect of β2-agonist treatment on insulin-stimulated peripheral glucose disposal in healthy men in a randomised placebo-controlled trial.
van Beek SMM, Bruls YMH, Vanweert F, Fealy CE, Connell NJ, Schaart G, Moonen-Kornips E, Jörgensen JA, Vaz FM, Smeets ETHC, Joris PJ, Gemmink A, Houtkooper RH, Hesselink MKC, Bengtsson T, Havekes B, Schrauwen P, Hoeks J. van Beek SMM, et al. Among authors: houtkooper rh. Nat Commun. 2023 Jan 12;14(1):173. doi: 10.1038/s41467-023-35798-5. Nat Commun. 2023. PMID: 36635304 Free PMC article. Clinical Trial.
184 results