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The transcription factor ZEB2 drives the formation of age-associated B cells.
Dai D, Gu S, Han X, Ding H, Jiang Y, Zhang X, Yao C, Hong S, Zhang J, Shen Y, Hou G, Qu B, Zhou H, Qin Y, He Y, Ma J, Yin Z, Ye Z, Qian J, Jiang Q, Wu L, Guo Q, Chen S, Huang C, Kottyan LC, Weirauch MT, Vinuesa CG, Shen N. Dai D, et al. Among authors: hou g. Science. 2024 Jan 26;383(6681):413-421. doi: 10.1126/science.adf8531. Epub 2024 Jan 25. Science. 2024. PMID: 38271512
Association of Abnormal Elevations in IFIT3 With Overactive Cyclic GMP-AMP Synthase/Stimulator of Interferon Genes Signaling in Human Systemic Lupus Erythematosus Monocytes.
Wang J, Dai M, Cui Y, Hou G, Deng J, Gao X, Liao Z, Liu Y, Meng Y, Wu L, Yao C, Wang Y, Qian J, Guo Q, Ding H, Qu B, Shen N. Wang J, et al. Among authors: hou g. Arthritis Rheumatol. 2018 Dec;70(12):2036-2045. doi: 10.1002/art.40576. Epub 2018 Oct 14. Arthritis Rheumatol. 2018. PMID: 29806091
Identification of Renal Long Non-coding RNA RP11-2B6.2 as a Positive Regulator of Type I Interferon Signaling Pathway in Lupus Nephritis.
Liao Z, Ye Z, Xue Z, Wu L, Ouyang Y, Yao C, Cui C, Xu N, Ma J, Hou G, Wang J, Meng Y, Yin Z, Liu Y, Qian J, Zhang C, Ding H, Guo Q, Qu B, Shen N. Liao Z, et al. Among authors: hou g. Front Immunol. 2019 May 3;10:975. doi: 10.3389/fimmu.2019.00975. eCollection 2019. Front Immunol. 2019. PMID: 31130957 Free PMC article.
SLE non-coding genetic risk variant determines the epigenetic dysfunction of an immune cell specific enhancer that controls disease-critical microRNA expression.
Hou G, Harley ITW, Lu X, Zhou T, Xu N, Yao C, Qin Y, Ouyang Y, Ma J, Zhu X, Yu X, Xu H, Dai D, Ding H, Yin Z, Ye Z, Deng J, Zhou M, Tang Y, Namjou B, Guo Y, Weirauch MT, Kottyan LC, Harley JB, Shen N. Hou G, et al. Nat Commun. 2021 Jan 8;12(1):135. doi: 10.1038/s41467-020-20460-1. Nat Commun. 2021. PMID: 33420081 Free PMC article.
Lupus enhancer risk variant causes dysregulation of IRF8 through cooperative lncRNA and DNA methylation machinery.
Zhou T, Zhu X, Ye Z, Wang YF, Yao C, Xu N, Zhou M, Ma J, Qin Y, Shen Y, Tang Y, Yin Z, Xu H, Zhang Y, Zang X, Ding H, Yang W, Guo Y, Harley JB, Namjou B, Kaufman KM, Kottyan LC, Weirauch MT, Hou G, Shen N. Zhou T, et al. Among authors: hou g. Nat Commun. 2022 Apr 6;13(1):1855. doi: 10.1038/s41467-022-29514-y. Nat Commun. 2022. PMID: 35388006 Free PMC article.
1,938 results