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In vivo reprogramming leads to premature death linked to hepatic and intestinal failure.
Parras A, Vílchez-Acosta A, Desdín-Micó G, Picó S, Mrabti C, Montenegro-Borbolla E, Maroun CY, Haghani A, Brooke R, Del Carmen Maza M, Rechsteiner C, Battiston F, Branchina C, Perez K, Horvath S, Bertelli C, Sempoux C, Ocampo A. Parras A, et al. Among authors: horvath s. Nat Aging. 2023 Dec;3(12):1509-1520. doi: 10.1038/s43587-023-00528-5. Epub 2023 Nov 27. Nat Aging. 2023. PMID: 38012287
Reversal of epigenetic aging and immunosenescent trends in humans.
Fahy GM, Brooke RT, Watson JP, Good Z, Vasanawala SS, Maecker H, Leipold MD, Lin DTS, Kobor MS, Horvath S. Fahy GM, et al. Among authors: horvath s. Aging Cell. 2019 Dec;18(6):e13028. doi: 10.1111/acel.13028. Epub 2019 Sep 8. Aging Cell. 2019. PMID: 31496122 Free PMC article.
Reprogramming to recover youthful epigenetic information and restore vision.
Lu Y, Brommer B, Tian X, Krishnan A, Meer M, Wang C, Vera DL, Zeng Q, Yu D, Bonkowski MS, Yang JH, Zhou S, Hoffmann EM, Karg MM, Schultz MB, Kane AE, Davidsohn N, Korobkina E, Chwalek K, Rajman LA, Church GM, Hochedlinger K, Gladyshev VN, Horvath S, Levine ME, Gregory-Ksander MS, Ksander BR, He Z, Sinclair DA. Lu Y, et al. Among authors: horvath s. Nature. 2020 Dec;588(7836):124-129. doi: 10.1038/s41586-020-2975-4. Epub 2020 Dec 2. Nature. 2020. PMID: 33268865 Free PMC article.
DNA methylation predicts age and provides insight into exceptional longevity of bats.
Wilkinson GS, Adams DM, Haghani A, Lu AT, Zoller J, Breeze CE, Arnold BD, Ball HC, Carter GG, Cooper LN, Dechmann DKN, Devanna P, Fasel NJ, Galazyuk AV, Günther L, Hurme E, Jones G, Knörnschild M, Lattenkamp EZ, Li CZ, Mayer F, Reinhardt JA, Medellin RA, Nagy M, Pope B, Power ML, Ransome RD, Teeling EC, Vernes SC, Zamora-Mejías D, Zhang J, Faure PA, Greville LJ, Herrera M LG, Flores-Martínez JJ, Horvath S. Wilkinson GS, et al. Among authors: horvath s. Nat Commun. 2021 Mar 12;12(1):1615. doi: 10.1038/s41467-021-21900-2. Nat Commun. 2021. PMID: 33712580 Free PMC article.
Author Correction: DNA methylation predicts age and provides insight into exceptional longevity of bats.
Wilkinson GS, Adams DM, Haghani A, Lu AT, Zoller J, Breeze CE, Arnold BD, Ball HC, Carter GG, Cooper LN, Dechmann DKN, Devanna P, Fasel NJ, Galazyuk AV, Günther L, Hurme E, Jones G, Knörnschild M, Lattenkamp EZ, Li CZ, Mayer F, Reinhardt JA, Medellin RA, Nagy M, Pope B, Power ML, Ransome RD, Teeling EC, Vernes SC, Zamora-Mejías D, Zhang J, Faure PA, Greville LJ, Horvath S, Herrera M LG, Flores-Martínez JJ. Wilkinson GS, et al. Among authors: horvath s. Nat Commun. 2021 May 5;12(1):2652. doi: 10.1038/s41467-021-23129-5. Nat Commun. 2021. PMID: 33953189 Free PMC article. No abstract available.
Epigenetic clock and methylation studies in elephants.
Prado NA, Brown JL, Zoller JA, Haghani A, Yao M, Bagryanova LR, Campana MG, E Maldonado J, Raj K, Schmitt D, Robeck TR, Horvath S. Prado NA, et al. Among authors: horvath s. Aging Cell. 2021 Jul;20(7):e13414. doi: 10.1111/acel.13414. Epub 2021 Jun 12. Aging Cell. 2021. PMID: 34118182 Free PMC article.
DNA methylation age analysis of rapamycin in common marmosets.
Horvath S, Zoller JA, Haghani A, Lu AT, Raj K, Jasinska AJ, Mattison JA, Salmon AB. Horvath S, et al. Geroscience. 2021 Oct;43(5):2413-2425. doi: 10.1007/s11357-021-00438-7. Epub 2021 Sep 5. Geroscience. 2021. PMID: 34482522 Free PMC article.
Epigenetic clock and DNA methylation analysis of porcine models of aging and obesity.
Schachtschneider KM, Schook LB, Meudt JJ, Shanmuganayagam D, Zoller JA, Haghani A, Li CZ, Zhang J, Yang A, Raj K, Horvath S. Schachtschneider KM, et al. Among authors: horvath s. Geroscience. 2021 Oct;43(5):2467-2483. doi: 10.1007/s11357-021-00439-6. Epub 2021 Sep 15. Geroscience. 2021. PMID: 34523051 Free PMC article.
1,277 results