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High-potency ligands for DREADD imaging and activation in rodents and monkeys.
Bonaventura J, Eldridge MAG, Hu F, Gomez JL, Sanchez-Soto M, Abramyan AM, Lam S, Boehm MA, Ruiz C, Farrell MR, Moreno A, Galal Faress IM, Andersen N, Lin JY, Moaddel R, Morris PJ, Shi L, Sibley DR, Mahler SV, Nabavi S, Pomper MG, Bonci A, Horti AG, Richmond BJ, Michaelides M. Bonaventura J, et al. Among authors: horti ag. Nat Commun. 2019 Oct 11;10(1):4627. doi: 10.1038/s41467-019-12236-z. Nat Commun. 2019. PMID: 31604917 Free PMC article.
Human brain imaging of α7 nAChR with [(18)F]ASEM: a new PET radiotracer for neuropsychiatry and determination of drug occupancy.
Wong DF, Kuwabara H, Pomper M, Holt DP, Brasic JR, George N, Frolov B, Willis W, Gao Y, Valentine H, Nandi A, Gapasin L, Dannals RF, Horti AG. Wong DF, et al. Among authors: horti ag. Mol Imaging Biol. 2014 Oct;16(5):730-8. doi: 10.1007/s11307-014-0779-3. Mol Imaging Biol. 2014. PMID: 25145965 Free PMC article. Clinical Trial.
[(125)I]Iodo-ASEM, a specific in vivo radioligand for α7-nAChR.
Gao Y, Mease RC, Olson TT, Kellar KJ, Dannals RF, Pomper MG, Horti AG. Gao Y, et al. Among authors: horti ag. Nucl Med Biol. 2015 May;42(5):488-493. doi: 10.1016/j.nucmedbio.2014.12.008. Epub 2014 Dec 20. Nucl Med Biol. 2015. PMID: 25687449 Free PMC article.
Cannabinoid CB2 Receptors in a Mouse Model of Aβ Amyloidosis: Immunohistochemical Analysis and Suitability as a PET Biomarker of Neuroinflammation.
Savonenko AV, Melnikova T, Wang Y, Ravert H, Gao Y, Koppel J, Lee D, Pletnikova O, Cho E, Sayyida N, Hiatt A, Troncoso J, Davies P, Dannals RF, Pomper MG, Horti AG. Savonenko AV, et al. Among authors: horti ag. PLoS One. 2015 Jun 18;10(6):e0129618. doi: 10.1371/journal.pone.0129618. eCollection 2015. PLoS One. 2015. PMID: 26086915 Free PMC article.
18F-FNDP for PET Imaging of Soluble Epoxide Hydrolase.
Horti AG, Wang Y, Minn I, Lan X, Wang J, Koehler RC, Alkayed NJ, Dannals RF, Pomper MG. Horti AG, et al. J Nucl Med. 2016 Nov;57(11):1817-1822. doi: 10.2967/jnumed.116.173245. Epub 2016 Jul 14. J Nucl Med. 2016. PMID: 27417650 Free PMC article.
Development of a High-Affinity PET Radioligand for Imaging Cannabinoid Subtype 2 Receptor.
Moldovan RP, Teodoro R, Gao Y, Deuther-Conrad W, Kranz M, Wang Y, Kuwabara H, Nakano M, Valentine H, Fischer S, Pomper MG, Wong DF, Dannals RF, Brust P, Horti AG. Moldovan RP, et al. Among authors: horti ag. J Med Chem. 2016 Sep 8;59(17):7840-55. doi: 10.1021/acs.jmedchem.6b00554. Epub 2016 Aug 23. J Med Chem. 2016. PMID: 27500461
95 results