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Ryanodine receptor leak triggers fiber Ca2+ redistribution to preserve force and elevate basal metabolism in skeletal muscle.
Lamboley CR, Pearce L, Seng C, Meizoso-Huesca A, Singh DP, Frankish BP, Kaura V, Lo HP, Ferguson C, Allen PD, Hopkins PM, Parton RG, Murphy RM, van der Poel C, Barclay CJ, Launikonis BS. Lamboley CR, et al. Among authors: hopkins pm. Sci Adv. 2021 Oct 29;7(44):eabi7166. doi: 10.1126/sciadv.abi7166. Epub 2021 Oct 27. Sci Adv. 2021. PMID: 34705503 Free PMC article.
Malignant hyperthermia susceptibility arising from altered resting coupling between the skeletal muscle L-type Ca2+ channel and the type 1 ryanodine receptor.
Eltit JM, Bannister RA, Moua O, Altamirano F, Hopkins PM, Pessah IN, Molinski TF, López JR, Beam KG, Allen PD. Eltit JM, et al. Among authors: hopkins pm. Proc Natl Acad Sci U S A. 2012 May 15;109(20):7923-8. doi: 10.1073/pnas.1119207109. Epub 2012 Apr 30. Proc Natl Acad Sci U S A. 2012. PMID: 22547813 Free PMC article.
Assessing the pathogenicity of RYR1 variants in malignant hyperthermia.
Merritt A, Booms P, Shaw MA, Miller DM, Daly C, Bilmen JG, Stowell KM, Allen PD, Steele DS, Hopkins PM. Merritt A, et al. Among authors: hopkins pm. Br J Anaesth. 2017 Apr 1;118(4):533-543. doi: 10.1093/bja/aex042. Br J Anaesth. 2017. PMID: 28403410 Free PMC article.
Sevoflurane may not be a complete sigh of relief in COVID-19.
Kaura V, Hopkins PM. Kaura V, et al. Among authors: hopkins pm. Br J Anaesth. 2020 Dec;125(6):e487-e488. doi: 10.1016/j.bja.2020.09.012. Epub 2020 Sep 16. Br J Anaesth. 2020. PMID: 33012516 Free PMC article. No abstract available.
257 results