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Fibroblast Activation Protein α-Targeted CD40 Agonism Abrogates Systemic Toxicity and Enables Administration of High Doses to Induce Effective Antitumor Immunity.
Sum E, Rapp M, Fröbel P, Le Clech M, Dürr H, Giusti AM, Perro M, Speziale D, Kunz L, Menietti E, Brünker P, Hopfer U, Lechmann M, Sobieniecki A, Appelt B, Adelfio R, Nicolini V, Freimoser-Grundschober A, Jordaan W, Labiano S, Weber F, Emrich T, Christen F, Essig B, Romero P, Trumpfheller C, Umaña P. Sum E, et al. Among authors: hopfer u. Clin Cancer Res. 2021 Jul 15;27(14):4036-4053. doi: 10.1158/1078-0432.CCR-20-4001. Epub 2021 Mar 26. Clin Cancer Res. 2021. PMID: 33771854
VEGF-mediated angiogenesis links EMT-induced cancer stemness to tumor initiation.
Fantozzi A, Gruber DC, Pisarsky L, Heck C, Kunita A, Yilmaz M, Meyer-Schaller N, Cornille K, Hopfer U, Bentires-Alj M, Christofori G. Fantozzi A, et al. Among authors: hopfer u. Cancer Res. 2014 Mar 1;74(5):1566-75. doi: 10.1158/0008-5472.CAN-13-1641. Epub 2014 Jan 10. Cancer Res. 2014. PMID: 24413534 Free article.
Prion protein functions as a ferrireductase partner for ZIP14 and DMT1.
Tripathi AK, Haldar S, Qian J, Beserra A, Suda S, Singh A, Hopfer U, Chen SG, Garrick MD, Turner JR, Knutson MD, Singh N. Tripathi AK, et al. Among authors: hopfer u. Free Radic Biol Med. 2015 Jul;84:322-330. doi: 10.1016/j.freeradbiomed.2015.03.037. Epub 2015 Apr 8. Free Radic Biol Med. 2015. PMID: 25862412 Free PMC article.
Prion protein promotes kidney iron uptake via its ferrireductase activity.
Haldar S, Tripathi A, Qian J, Beserra A, Suda S, McElwee M, Turner J, Hopfer U, Singh N. Haldar S, et al. Among authors: hopfer u. J Biol Chem. 2015 Feb 27;290(9):5512-22. doi: 10.1074/jbc.M114.607507. Epub 2015 Jan 8. J Biol Chem. 2015. PMID: 25572394 Free PMC article.
174 results