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PSGL-1 attenuates early TCR signaling to suppress CD8+ T cell progenitor differentiation and elicit terminal CD8+ T cell exhaustion.
Hope JL, Otero DC, Bae EA, Stairiker CJ, Palete AB, Faso HA, Lin M, Henriquez ML, Roy S, Seo H, Lei X, Wang ES, Chow S, Tinoco R, Daniels GA, Yip K, Campos AR, Yin J, Adams PD, Rao A, Bradley LM. Hope JL, et al. Cell Rep. 2023 May 30;42(5):112436. doi: 10.1016/j.celrep.2023.112436. Epub 2023 Apr 26. Cell Rep. 2023. PMID: 37115668 Free PMC article.
Lessons in antiviral immunity.
Hope JL, Bradley LM. Hope JL, et al. Science. 2021 Jan 29;371(6528):464-465. doi: 10.1126/science.abf6446. Science. 2021. PMID: 33510014 No abstract available.
MicroRNA-139 Expression Is Dispensable for the Generation of Influenza-Specific CD8+ T Cell Responses.
Hope JL, Zhao M, Stairiker CJ, Kiernan CH, Carey AJ, Mueller YM, van Meurs M, Brouwers-Haspels I, Otero DC, Bae EA, Faso HA, Maas A, de Looper H, Fortina PM, Rigoutsos I, Bradley LM, Erkeland SJ, Katsikis PD. Hope JL, et al. J Immunol. 2022 Feb 1;208(3):603-617. doi: 10.4049/jimmunol.2000621. Epub 2022 Jan 12. J Immunol. 2022. PMID: 35022277 Free PMC article.
FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells.
Shen JZ, Qiu Z, Wu Q, Finlay D, Garcia G, Sun D, Rantala J, Barshop W, Hope JL, Gimple RC, Sangfelt O, Bradley LM, Wohlschlegel J, Rich JN, Spruck C. Shen JZ, et al. Among authors: hope jl. Cell. 2021 Jan 21;184(2):352-369.e23. doi: 10.1016/j.cell.2020.11.042. Epub 2020 Dec 23. Cell. 2021. PMID: 33357448 Free PMC article.
Rapid in vitro generation of bona fide exhausted CD8+ T cells is accompanied by Tcf7 promotor methylation.
Zhao M, Kiernan CH, Stairiker CJ, Hope JL, Leon LG, van Meurs M, Brouwers-Haspels I, Boers R, Boers J, Gribnau J, van IJcken WFJ, Bindels EM, Hoogenboezem RM, Erkeland SJ, Mueller YM, Katsikis PD. Zhao M, et al. Among authors: hope jl. PLoS Pathog. 2020 Jun 24;16(6):e1008555. doi: 10.1371/journal.ppat.1008555. eCollection 2020 Jun. PLoS Pathog. 2020. PMID: 32579593 Free PMC article.
The Transcription Factor T-Bet Is Regulated by MicroRNA-155 in Murine Anti-Viral CD8+ T Cells via SHIP-1.
Hope JL, Stairiker CJ, Spantidea PI, Gracias DT, Carey AJ, Fike AJ, van Meurs M, Brouwers-Haspels I, Rijsbergen LC, Fraietta JA, Mueller YM, Klop RC, Stelekati E, Wherry EJ, Erkeland SJ, Katsikis PD. Hope JL, et al. Front Immunol. 2017 Dec 6;8:1696. doi: 10.3389/fimmu.2017.01696. eCollection 2017. Front Immunol. 2017. PMID: 29358931 Free PMC article.
Acute exposure to ZnO nanoparticles induces autophagic immune cell death.
Johnson BM, Fraietta JA, Gracias DT, Hope JL, Stairiker CJ, Patel PR, Mueller YM, McHugh MD, Jablonowski LJ, Wheatley MA, Katsikis PD. Johnson BM, et al. Among authors: hope jl. Nanotoxicology. 2015;9(6):737-48. doi: 10.3109/17435390.2014.974709. Epub 2014 Nov 7. Nanotoxicology. 2015. PMID: 25378273
27 results