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DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance.
Schröder M, Renatus M, Liang X, Meili F, Zoller T, Ferrand S, Gauter F, Li X, Sigoillot F, Gleim S, Stachyra TM, Thomas JR, Begue D, Khoshouei M, Lefeuvre P, Andraos-Rey R, Chung B, Ma R, Pinch B, Hofmann A, Schirle M, Schmiedeberg N, Imbach P, Gorses D, Calkins K, Bauer-Probst B, Maschlej M, Niederst M, Maher R, Henault M, Alford J, Ahrne E, Tordella L, Hollingworth G, Thomä NH, Vulpetti A, Radimerski T, Holzer P, Carbonneau S, Thoma CR. Schröder M, et al. Among authors: holzer p. Nat Commun. 2024 Jan 4;15(1):275. doi: 10.1038/s41467-023-44237-4. Nat Commun. 2024. PMID: 38177131 Free PMC article.
Power games in Austrian science.
Holzer P. Holzer P. Nature. 1996 Dec 5;384(6608):404. doi: 10.1038/384404c0. Nature. 1996. PMID: 8945459 No abstract available.
Enhanced Donor Antigen Presentation by B Cells Predicts Acute Cellular Rejection and Late Outcomes After Transplantation.
Ashokkumar C, Ningappa M, Raghu V, Mazariegos G, Higgs BW, Morgan P, Remaley L, Fazzolare Martin T, Holzer P, Trostle K, Xu Q, Zeevi A, Squires J, Soltys K, Horslen S, Khanna A, Ganoza A, Sindhi R. Ashokkumar C, et al. Among authors: holzer p. Transplant Direct. 2024 Feb 26;10(3):e1589. doi: 10.1097/TXD.0000000000001589. eCollection 2024 Mar. Transplant Direct. 2024. PMID: 38414976 Free PMC article.
Placental Pathology Findings in Unexplained Pregnancy Losses.
Thompson BB, Holzer PH, Kliman HJ. Thompson BB, et al. Among authors: holzer ph. Reprod Sci. 2024 Feb;31(2):488-504. doi: 10.1007/s43032-023-01344-3. Epub 2023 Sep 19. Reprod Sci. 2024. PMID: 37725247 Free PMC article.
Discovery of New Binders for DCAF1, an Emerging Ligase Target in the Targeted Protein Degradation Field.
Vulpetti A, Holzer P, Schmiedeberg N, Imbach-Weese P, Pissot-Soldermann C, Hollingworth GJ, Radimerski T, Thoma CR, Stachyra TM, Wojtynek M, Maschlej M, Chau S, Schuffenhauer A, Fernández C, Schröder M, Renatus M. Vulpetti A, et al. Among authors: holzer p. ACS Med Chem Lett. 2023 Jun 2;14(7):949-954. doi: 10.1021/acsmedchemlett.3c00104. eCollection 2023 Jul 13. ACS Med Chem Lett. 2023. PMID: 37465299
Large-gap peripheral nerve repair using xenogeneic transplants in rhesus macaques.
Holzer P, Chang EJ, Rogers K, Tarlton J, Lu D, Gillespie N, Adkins J, Metea M, LaRochelle A, Wicks J, Onel B, Gullans S, Doloff JC, Scobie L, Cetrulo CL Jr, Monroy R. Holzer P, et al. Xenotransplantation. 2023 Mar;30(2):e12792. doi: 10.1111/xen.12792. Epub 2023 Jan 17. Xenotransplantation. 2023. PMID: 36648004
Trophoblast inclusions and adverse birth outcomes.
Firestein MR, Kliman HJ, Sania A, Brink LT, Holzer PH, Hofmann KM, Milano KM, Pini N, Shuffrey LC, Odendaal HJ, Fifer WP. Firestein MR, et al. Among authors: holzer ph. PLoS One. 2022 Mar 1;17(3):e0264733. doi: 10.1371/journal.pone.0264733. eCollection 2022. PLoS One. 2022. PMID: 35231069 Free PMC article.
376 results