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Telomeres and Longevity: A Cause or an Effect?
Adwan Shekhidem H, Sharvit L, Leman E, Manov I, Roichman A, Holtze S, M Huffman D, Y Cohen H, Bernd Hildebrandt T, Shams I, Atzmon G. Adwan Shekhidem H, et al. Among authors: holtze s. Int J Mol Sci. 2019 Jul 1;20(13):3233. doi: 10.3390/ijms20133233. Int J Mol Sci. 2019. PMID: 31266154 Free PMC article.
Low sulfide levels and a high degree of cystathionine β-synthase (CBS) activation by S-adenosylmethionine (SAM) in the long-lived naked mole-rat.
Dziegelewska M, Holtze S, Vole C, Wachter U, Menzel U, Morhart M, Groth M, Szafranski K, Sahm A, Sponholz C, Dammann P, Huse K, Hildebrandt T, Platzer M. Dziegelewska M, et al. Among authors: holtze s. Redox Biol. 2016 Aug;8:192-8. doi: 10.1016/j.redox.2016.01.008. Epub 2016 Jan 14. Redox Biol. 2016. PMID: 26803480 Free PMC article.
Neoteny, Prolongation of Youth: From Naked Mole Rats to "Naked Apes" (Humans).
Skulachev VP, Holtze S, Vyssokikh MY, Bakeeva LE, Skulachev MV, Markov AV, Hildebrandt TB, Sadovnichii VA. Skulachev VP, et al. Among authors: holtze s. Physiol Rev. 2017 Apr;97(2):699-720. doi: 10.1152/physrev.00040.2015. Physiol Rev. 2017. PMID: 28202600 Free article. Review.
Long-lived rodents reveal signatures of positive selection in genes associated with lifespan.
Sahm A, Bens M, Szafranski K, Holtze S, Groth M, Görlach M, Calkhoven C, Müller C, Schwab M, Kraus J, Kestler HA, Cellerino A, Burda H, Hildebrandt T, Dammann P, Platzer M. Sahm A, et al. Among authors: holtze s. PLoS Genet. 2018 Mar 23;14(3):e1007272. doi: 10.1371/journal.pgen.1007272. eCollection 2018 Mar. PLoS Genet. 2018. PMID: 29570707 Free PMC article.
Mild depolarization of the inner mitochondrial membrane is a crucial component of an anti-aging program.
Vyssokikh MY, Holtze S, Averina OA, Lyamzaev KG, Panteleeva AA, Marey MV, Zinovkin RA, Severin FF, Skulachev MV, Fasel N, Hildebrandt TB, Skulachev VP. Vyssokikh MY, et al. Among authors: holtze s. Proc Natl Acad Sci U S A. 2020 Mar 24;117(12):6491-6501. doi: 10.1073/pnas.1916414117. Epub 2020 Mar 9. Proc Natl Acad Sci U S A. 2020. PMID: 32152094 Free PMC article.
58 results