Holinstat MA - Search Results

1

Ectonucleotidase tri(di)phosphohydrolase-1 (ENTPD-1) disrupts inflammasome/interleukin 1β-driven venous thrombosis.

Yadav V, Chi L, Zhao R, Tourdot BE, Yalavarthi S, Jacobs BN, Banka A, Liao H, Koonse S, Anyanwu AC, Visovatti SH, Holinstat MA, Kahlenberg JM, Knight JS, Pinsky DJ, Kanthi Y. Yadav V, et al. Among authors: holinstat ma. J Clin Invest. 2019 Apr 16;129(7):2872-2877. doi: 10.1172/JCI124804. J Clin Invest. 2019. PMID: 30990798 Free PMC article.

2

Cryo-EM structures of human arachidonate 12S-lipoxygenase bound to endogenous and exogenous inhibitors.

Mobbs JI, Black KA, Tran M, Burger WAC, Venugopal H, Holman TR, Holinstat M, Thal DM, Glukhova A. Mobbs JI, et al. Blood. 2023 Oct 5;142(14):1233-1242. doi: 10.1182/blood.2023020441. Blood. 2023. PMID: 37506345

3

The emerging role of oxylipins in thrombosis and diabetes.

Tourdot BE, Ahmed I, Holinstat M. Tourdot BE, et al. Front Pharmacol. 2014 Jan 7;4:176. doi: 10.3389/fphar.2013.00176. eCollection 2014 Jan 7. Front Pharmacol. 2014. PMID: 24432004 Free PMC article. Review.

4

Coronary heart disease risk factors take a disproportional toll on women.

Holinstat M, Tourdot BE. Holinstat M, et al. Arterioscler Thromb Vasc Biol. 2015 Apr;35(4):750-1. doi: 10.1161/ATVBAHA.115.305466. Arterioscler Thromb Vasc Biol. 2015. PMID: 25810295 Free PMC article. No abstract available.

5

12(S)-HETrE, a 12-Lipoxygenase Oxylipin of Dihomo-γ-Linolenic Acid, Inhibits Thrombosis via Gαs Signaling in Platelets.

Yeung J, Tourdot BE, Adili R, Green AR, Freedman CJ, Fernandez-Perez P, Yu J, Holman TR, Holinstat M. Yeung J, et al. Arterioscler Thromb Vasc Biol. 2016 Oct;36(10):2068-77. doi: 10.1161/ATVBAHA.116.308050. Epub 2016 Jul 28. Arterioscler Thromb Vasc Biol. 2016. PMID: 27470510 Free PMC article.

6

First Selective 12-LOX Inhibitor, ML355, Impairs Thrombus Formation and Vessel Occlusion In Vivo With Minimal Effects on Hemostasis.

Adili R, Tourdot BE, Mast K, Yeung J, Freedman JC, Green A, Luci DK, Jadhav A, Simeonov A, Maloney DJ, Holman TR, Holinstat M. Adili R, et al. Arterioscler Thromb Vasc Biol. 2017 Oct;37(10):1828-1839. doi: 10.1161/ATVBAHA.117.309868. Epub 2017 Aug 3. Arterioscler Thromb Vasc Biol. 2017. PMID: 28775075 Free PMC article.

7

Targeting 12-Lipoxygenase as a Potential Novel Antiplatelet Therapy.

Tourdot BE, Holinstat M. Tourdot BE, et al. Trends Pharmacol Sci. 2017 Nov;38(11):1006-1015. doi: 10.1016/j.tips.2017.08.001. Epub 2017 Aug 29. Trends Pharmacol Sci. 2017. PMID: 28863985 Review.

8

12-HETrE inhibits platelet reactivity and thrombosis in part through the prostacyclin receptor.

Tourdot BE, Adili R, Isingizwe ZR, Ebrahem M, Freedman JC, Holman TR, Holinstat M. Tourdot BE, et al. Blood Adv. 2017 Jun 23;1(15):1124-1131. doi: 10.1182/bloodadvances.2017006155. eCollection 2017 Jun 27. Blood Adv. 2017. PMID: 29296755 Free PMC article.

9

Genetic Variant in Human PAR (Protease-Activated Receptor) 4 Enhances Thrombus Formation Resulting in Resistance to Antiplatelet Therapeutics.

Tourdot BE, Stoveken H, Trumbo D, Yeung J, Kanthi Y, Edelstein LC, Bray PF, Tall GG, Holinstat M. Tourdot BE, et al. Arterioscler Thromb Vasc Biol. 2018 Jul;38(7):1632-1643. doi: 10.1161/ATVBAHA.118.311112. Epub 2018 May 10. Arterioscler Thromb Vasc Biol. 2018. PMID: 29748334 Free PMC article.

10

5 S,15 S-Dihydroperoxyeicosatetraenoic Acid (5,15-diHpETE) as a Lipoxin Intermediate: Reactivity and Kinetics with Human Leukocyte 5-Lipoxygenase, Platelet 12-Lipoxygenase, and Reticulocyte 15-Lipoxygenase-1.

Green AR, Freedman C, Tena J, Tourdot BE, Liu B, Holinstat M, Holman TR. Green AR, et al. Biochemistry. 2018 Dec 4;57(48):6726-6734. doi: 10.1021/acs.biochem.8b00889. Epub 2018 Nov 15. Biochemistry. 2018. PMID: 30407793 Free PMC article.

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