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How can fluorine directly and indirectly affect the hydrogen bonding in molecular systems? - A case study for monofluoroanilines.
Pietruś W, Kurczab R, Kafel R, Machalska E, Kalinowska-Tłuścik J, Hogendorf A, Żylewski M, Baranska M, Bojarski AJ. Pietruś W, et al. Among authors: hogendorf a. Spectrochim Acta A Mol Biomol Spectrosc. 2021 May 5;252:119536. doi: 10.1016/j.saa.2021.119536. Epub 2021 Feb 3. Spectrochim Acta A Mol Biomol Spectrosc. 2021. PMID: 33588362
Pyrano[2,3,4-cd]indole as a Scaffold for Selective Nonbasic 5-HT6R Ligands.
Staroń J, Mordalski S, Warszycki D, Satała G, Hogendorf A, Bojarski AJ. Staroń J, et al. Among authors: hogendorf a. ACS Med Chem Lett. 2017 Mar 27;8(4):390-394. doi: 10.1021/acsmedchemlett.6b00482. eCollection 2017 Apr 13. ACS Med Chem Lett. 2017. PMID: 28435524 Free PMC article.
Low-basicity 5-HT7 Receptor Agonists Synthesized Using the van Leusen Multicomponent Protocol.
Hogendorf AS, Hogendorf A, Kurczab R, Satała G, Lenda T, Walczak M, Latacz G, Handzlik J, Kieć-Kononowicz K, Wierońska JM, Woźniak M, Cieślik P, Bugno R, Staroń J, Bojarski AJ. Hogendorf AS, et al. Among authors: hogendorf a. Sci Rep. 2017 May 4;7(1):1444. doi: 10.1038/s41598-017-00822-4. Sci Rep. 2017. PMID: 28473721 Free PMC article.
Design, synthesis, and biological evaluation of novel combretastatin A-4 thio derivatives as microtubule targeting agents.
Stefański T, Mikstacka R, Kurczab R, Dutkiewicz Z, Kucińska M, Murias M, Zielińska-Przyjemska M, Cichocki M, Teubert A, Kaczmarek M, Hogendorf A, Sobiak S. Stefański T, et al. Among authors: hogendorf a. Eur J Med Chem. 2018 Jan 20;144:797-816. doi: 10.1016/j.ejmech.2017.11.050. Epub 2017 Dec 12. Eur J Med Chem. 2018. PMID: 29291446
Search for a 5-CT alternative. In vitro and in vivo evaluation of novel pharmacological tools: 3-(1-alkyl-1H-imidazol-5-yl)-1H-indole-5-carboxamides, low-basicity 5-HT7 receptor agonists.
Latacz G, Hogendorf AS, Hogendorf A, Lubelska A, Wierońska JM, Woźniak M, Cieślik P, Kieć-Kononowicz K, Handzlik J, Bojarski AJ. Latacz G, et al. Among authors: hogendorf as, hogendorf a. Medchemcomm. 2018 Sep 25;9(11):1882-1890. doi: 10.1039/c8md00313k. eCollection 2018 Nov 1. Medchemcomm. 2018. PMID: 30568756 Free PMC article.
Fluorinated indole-imidazole conjugates: Selective orally bioavailable 5-HT7 receptor low-basicity agonists, potential neuropathic painkillers.
Hogendorf AS, Hogendorf A, Popiołek-Barczyk K, Ciechanowska A, Mika J, Satała G, Walczak M, Latacz G, Handzlik J, Kieć-Kononowicz K, Ponimaskin E, Schade S, Zeug A, Bijata M, Kubicki M, Kurczab R, Lenda T, Staroń J, Bugno R, Duszyńska B, Pilarski B, Bojarski AJ. Hogendorf AS, et al. Among authors: hogendorf a. Eur J Med Chem. 2019 May 15;170:261-275. doi: 10.1016/j.ejmech.2019.03.017. Epub 2019 Mar 11. Eur J Med Chem. 2019. PMID: 30904783
2-Aminoimidazole-based antagonists of the 5-HT6 receptor - A new concept in aminergic GPCR ligand design.
Hogendorf AS, Hogendorf A, Kurczab R, Kalinowska-Tłuścik J, Popik P, Nikiforuk A, Krawczyk M, Satała G, Lenda T, Knutelska J, Bugno R, Staroń J, Pietruś W, Matłoka M, Dubiel K, Moszczyński-Pętkowski R, Pieczykolan J, Wieczorek M, Pilarski B, Zajdel P, Bojarski AJ. Hogendorf AS, et al. Among authors: hogendorf a. Eur J Med Chem. 2019 Oct 1;179:1-15. doi: 10.1016/j.ejmech.2019.06.001. Epub 2019 Jun 5. Eur J Med Chem. 2019. PMID: 31229883
Virtual screening-driven discovery of dual 5-HT6/5-HT2A receptor ligands with pro-cognitive properties.
Staroń J, Kurczab R, Warszycki D, Satała G, Krawczyk M, Bugno R, Lenda T, Popik P, Hogendorf AS, Hogendorf A, Dubiel K, Matłoka M, Moszczyński-Pętkowski R, Pieczykolan J, Wieczorek M, Zajdel P, Bojarski AJ. Staroń J, et al. Among authors: hogendorf as, hogendorf a. Eur J Med Chem. 2020 Jan 1;185:111857. doi: 10.1016/j.ejmech.2019.111857. Epub 2019 Nov 7. Eur J Med Chem. 2020. PMID: 31734022 Free article.
Rationally designed N-phenylsulfonylindoles as a tool for the analysis of the non-basic 5-HT6R ligands binding mode.
Staroń J, Bugno R, Pietruś W, Satała G, Mordalski S, Warszycki D, Hogendorf A, Hogendorf AS, Kalinowska-Tłuścik J, Lenda T, Pilarski B, Bojarski AJ. Staroń J, et al. Among authors: hogendorf a, hogendorf as. Eur J Med Chem. 2021 Jan 1;209:112916. doi: 10.1016/j.ejmech.2020.112916. Epub 2020 Oct 9. Eur J Med Chem. 2021. PMID: 33328102
43 results