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A preclinical mouse model of glioma with an alternative mechanism of telomere maintenance (ALT).
Jeitany M, Pineda JR, Liu Q, Porreca RM, Hoffschir F, Desmaze C, Silvestre DC, Mailliet P, Junier MP, Londoño-Vallejo A, Ségal-Bendirdjian E, Chneiweiss H, Boussin FD. Jeitany M, et al. Among authors: hoffschir f. Int J Cancer. 2015 Apr 1;136(7):1546-58. doi: 10.1002/ijc.29171. Epub 2014 Sep 11. Int J Cancer. 2015. PMID: 25175359 Free PMC article.
Alternative lengthening of telomeres in human glioma stem cells.
Silvestre DC, Pineda JR, Hoffschir F, Studler JM, Mouthon MA, Pflumio F, Junier MP, Chneiweiss H, Boussin FD. Silvestre DC, et al. Among authors: hoffschir f. Stem Cells. 2011 Mar;29(3):440-51. doi: 10.1002/stem.600. Stem Cells. 2011. PMID: 21425407
Preferential binding of a G-quadruplex ligand to human chromosome ends.
Granotier C, Pennarun G, Riou L, Hoffschir F, Gauthier LR, De Cian A, Gomez D, Mandine E, Riou JF, Mergny JL, Mailliet P, Dutrillaux B, Boussin FD. Granotier C, et al. Among authors: hoffschir f. Nucleic Acids Res. 2005 Jul 28;33(13):4182-90. doi: 10.1093/nar/gki722. Print 2005. Nucleic Acids Res. 2005. PMID: 16052031 Free PMC article.
Role of ATM in the telomere response to the G-quadruplex ligand 360A.
Pennarun G, Granotier C, Hoffschir F, Mandine E, Biard D, Gauthier LR, Boussin FD. Pennarun G, et al. Among authors: hoffschir f. Nucleic Acids Res. 2008 Mar;36(5):1741-54. doi: 10.1093/nar/gkn026. Epub 2008 Feb 7. Nucleic Acids Res. 2008. PMID: 18263609 Free PMC article.
ATR contributes to telomere maintenance in human cells.
Pennarun G, Hoffschir F, Revaud D, Granotier C, Gauthier LR, Mailliet P, Biard DS, Boussin FD. Pennarun G, et al. Among authors: hoffschir f. Nucleic Acids Res. 2010 May;38(9):2955-63. doi: 10.1093/nar/gkp1248. Epub 2010 Feb 10. Nucleic Acids Res. 2010. PMID: 20147462 Free PMC article.
Rad51 and DNA-PKcs are involved in the generation of specific telomere aberrations induced by the quadruplex ligand 360A that impair mitotic cell progression and lead to cell death.
Gauthier LR, Granotier C, Hoffschir F, Etienne O, Ayouaz A, Desmaze C, Mailliet P, Biard DS, Boussin FD. Gauthier LR, et al. Among authors: hoffschir f. Cell Mol Life Sci. 2012 Feb;69(4):629-40. doi: 10.1007/s00018-011-0767-6. Epub 2011 Jul 20. Cell Mol Life Sci. 2012. PMID: 21773671 Free PMC article.
Role of Fanconi DNA repair pathway in neural stem cell homeostasis.
Sii-Felice K, Barroca V, Etienne O, Riou L, Hoffschir F, Fouchet P, Boussin FD, Mouthon MA. Sii-Felice K, et al. Among authors: hoffschir f. Cell Cycle. 2008 Jul 1;7(13):1911-5. doi: 10.4161/cc.7.13.6235. Epub 2008 May 5. Cell Cycle. 2008. PMID: 18604174
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