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Peripherally active dextromethorphan derivatives lower blood glucose levels by targeting pancreatic islets.
Scholz O, Otter S, Welters A, Wörmeyer L, Dolenšek J, Klemen MS, Pohorec V, Eberhard D, Mrugala J, Hamacher A, Koch A, Sanz M, Hoffmann T, Hogeback J, Herebian D, Klöcker N, Piechot A, Mayatepek E, Meissner T, Stožer A, Lammert E. Scholz O, et al. Among authors: hoffmann t. Cell Chem Biol. 2021 Oct 21;28(10):1474-1488.e7. doi: 10.1016/j.chembiol.2021.05.011. Epub 2021 Jun 11. Cell Chem Biol. 2021. PMID: 34118188 Free article.
Protection of pancreatic islets from oxidative cell death by a peripherally-active morphinan with increased drug safety.
Scholz O, Huß E, Otter S, Herebian D, Hamacher A, Levy LM, Hristeva S, Sanz M, Ajani H, Puentes AR, Hoffmann T, Hogeback J, Unger A, Terheyden S, Reina do Fundo M, Dewidar B, Roden M, Lammert E. Scholz O, et al. Among authors: hoffmann t. Mol Metab. 2023 Sep;75:101775. doi: 10.1016/j.molmet.2023.101775. Epub 2023 Jul 12. Mol Metab. 2023. PMID: 37451343 Free PMC article.
An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-κB-Utilizing a Reversible Covalent Tethering Approach.
Wolter M, Valenti D, Cossar PJ, Hristeva S, Levy LM, Genski T, Hoffmann T, Brunsveld L, Tzalis D, Ottmann C. Wolter M, et al. Among authors: hoffmann t. J Med Chem. 2021 Jun 24;64(12):8423-8436. doi: 10.1021/acs.jmedchem.1c00401. Epub 2021 Jun 2. J Med Chem. 2021. PMID: 34076416 Free PMC article.
Increase in acute mastoiditis at the end of the COVID-19 pandemic.
Goldberg-Bockhorn E, Hurzlmeier C, Vahl JM, Stupp F, Janda A, von Baum H, Hoffmann TK. Goldberg-Bockhorn E, et al. Among authors: hoffmann tk. Eur Arch Otorhinolaryngol. 2024 May 14. doi: 10.1007/s00405-024-08704-y. Online ahead of print. Eur Arch Otorhinolaryngol. 2024. PMID: 38740579
Development of a patient decision aid for children and adolescents following anterior cruciate ligament rupture: an international mixed-methods study.
Gamble AR, McKay MJ, Anderson DB, Pappas E, Alvarez Cooper I, Macpherson S, Harris IA, Filbay SR, McCaffery K, Thompson R, Hoffmann TC, Maher CG, Zadro JR. Gamble AR, et al. Among authors: hoffmann tc. BMJ Open. 2024 Apr 29;14(4):e081421. doi: 10.1136/bmjopen-2023-081421. BMJ Open. 2024. PMID: 38684251 Free PMC article.
1,708 results