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Use of the Cultex® Radial Flow System as an in vitro exposure method to assess acute pulmonary toxicity of fine dusts and nanoparticles with special focus on the intra- and inter-laboratory reproducibility.
Steinritz D, Möhle N, Pohl C, Papritz M, Stenger B, Schmidt A, Kirkpatrick CJ, Thiermann H, Vogel R, Hoffmann S, Aufderheide M. Steinritz D, et al. Among authors: hoffmann s. Chem Biol Interact. 2013 Dec 5;206(3):479-90. doi: 10.1016/j.cbi.2013.05.001. Epub 2013 May 11. Chem Biol Interact. 2013. PMID: 23669118
Validation study on the Ocular Irritection assay for eye irritation testing.
Eskes C, Hoffmann S, Facchini D, Ulmer R, Wang A, Flego M, Vassallo M, Bufo M, van Vliet E, d'Abrosca F, Wilt N. Eskes C, et al. Among authors: hoffmann s. Toxicol In Vitro. 2014 Aug;28(5):1046-65. doi: 10.1016/j.tiv.2014.02.009. Epub 2014 Mar 15. Toxicol In Vitro. 2014. PMID: 24637247 Free article.
Intra- and inter-laboratory reproducibility and accuracy of the LuSens assay: A reporter gene-cell line to detect keratinocyte activation by skin sensitizers.
Ramirez T, Stein N, Aumann A, Remus T, Edwards A, Norman KG, Ryan C, Bader JE, Fehr M, Burleson F, Foertsch L, Wang X, Gerberick F, Beilstein P, Hoffmann S, Mehling A, van Ravenzwaay B, Landsiedel R. Ramirez T, et al. Among authors: hoffmann s. Toxicol In Vitro. 2016 Apr;32:278-86. doi: 10.1016/j.tiv.2016.01.004. Epub 2016 Jan 12. Toxicol In Vitro. 2016. PMID: 26796489 Free article.
Exposure of 19 substances to lung A549 cells at the air liquid interface or under submerged conditions reveals high correlation between cytotoxicity in vitro and CLP classifications for acute lung toxicity.
Gohlsch K, Mückter H, Steinritz D, Aufderheide M, Hoffmann S, Gudermann T, Breit A. Gohlsch K, et al. Among authors: hoffmann s. Toxicol Lett. 2019 Nov;316:119-126. doi: 10.1016/j.toxlet.2019.09.014. Epub 2019 Sep 17. Toxicol Lett. 2019. PMID: 31539570
Inter-laboratory evaluation of the response of primary human hepatocyte cultures to model CYP inducers - a European Centre for Validation of Alternative Methods (ECVAM) - funded pre-validation study.
Richert L, Abadie C, Bonet A, Heyd B, Mantion G, Alexandre E, Bachellier P, Kingston S, Pattenden C, Illouz S, Dennison A, Hoffmann S, Coecke S. Richert L, et al. Among authors: hoffmann s. Toxicol In Vitro. 2010 Feb;24(1):335-45. doi: 10.1016/j.tiv.2009.05.022. Epub 2009 Jun 2. Toxicol In Vitro. 2010. PMID: 19497361
1,747 results