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Flukicidal effects of abietane diterpenoid derived analogues against the food borne pathogen Fasciola hepatica.
Chakroborty A, Pritchard D, Bouillon ME, Cervi A, Cookson A, Wild C, Fenn C, Payne J, Holdsworth P, Capner C, O'Neill J, Padalino G, Forde-Thomas J, Gupta S, Smith BG, Fisher M, Lahmann M, Baird MS, Hoffmann KF. Chakroborty A, et al. Among authors: hoffmann kf. Vet Parasitol. 2022 Sep;309:109766. doi: 10.1016/j.vetpar.2022.109766. Epub 2022 Jul 20. Vet Parasitol. 2022. PMID: 35926239 Free article.
(Epi)genetic Inheritance in Schistosoma mansoni: A Systems Approach.
Cosseau C, Wolkenhauer O, Padalino G, Geyer KK, Hoffmann KF, Grunau C. Cosseau C, et al. Among authors: hoffmann kf. Trends Parasitol. 2017 Apr;33(4):285-294. doi: 10.1016/j.pt.2016.12.002. Epub 2016 Dec 28. Trends Parasitol. 2017. PMID: 28040375 Free PMC article. Review.
Design, synthesis and anthelmintic activity of 7-keto-sempervirol analogues.
Crusco A, Bordoni C, Chakroborty A, Whatley KCL, Whiteland H, Westwell AD, Hoffmann KF. Crusco A, et al. Among authors: hoffmann kf. Eur J Med Chem. 2018 May 25;152:87-100. doi: 10.1016/j.ejmech.2018.04.032. Epub 2018 Apr 17. Eur J Med Chem. 2018. PMID: 29698860 Free article.
An Abies procera-derived tetracyclic triterpene containing a steroid-like nucleus core and a lactone side chain attenuates in vitro survival of both Fasciola hepatica and Schistosoma mansoni.
Whiteland HL, Chakroborty A, Forde-Thomas JE, Crusco A, Cookson A, Hollinshead J, Fenn CA, Bartholomew B, Holdsworth PA, Fisher M, Nash RJ, Hoffmann KF. Whiteland HL, et al. Among authors: hoffmann kf. Int J Parasitol Drugs Drug Resist. 2018 Dec;8(3):465-474. doi: 10.1016/j.ijpddr.2018.10.009. Epub 2018 Oct 26. Int J Parasitol Drugs Drug Resist. 2018. PMID: 30399512 Free PMC article.
Erratum to 'Combining bioinformatics, cheminformatics, functional genomics and whole organism approaches for identifying epigenetic drug targets in Schistosoma mansoni' [IJP Drugs Drug Resist. 8 (2018) 559-570].
Padalino G, Ferla S, Brancale A, Chalmers IW, Hoffmann KF. Padalino G, et al. Among authors: hoffmann kf. Int J Parasitol Drugs Drug Resist. 2019 Aug;10:91. doi: 10.1016/j.ijpddr.2019.07.001. Epub 2019 Jul 2. Int J Parasitol Drugs Drug Resist. 2019. PMID: 31299537 Free PMC article. No abstract available.
The repositioning of epigenetic probes/inhibitors identifies new anti-schistosomal lead compounds and chemotherapeutic targets.
Whatley KCL, Padalino G, Whiteland H, Geyer KK, Hulme BJ, Chalmers IW, Forde-Thomas J, Ferla S, Brancale A, Hoffmann KF. Whatley KCL, et al. Among authors: hoffmann kf. PLoS Negl Trop Dis. 2019 Nov 15;13(11):e0007693. doi: 10.1371/journal.pntd.0007693. eCollection 2019 Nov. PLoS Negl Trop Dis. 2019. PMID: 31730617 Free PMC article.
253 results