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A guiding map for inflammation.
Netea MG, Balkwill F, Chonchol M, Cominelli F, Donath MY, Giamarellos-Bourboulis EJ, Golenbock D, Gresnigt MS, Heneka MT, Hoffman HM, Hotchkiss R, Joosten LAB, Kastner DL, Korte M, Latz E, Libby P, Mandrup-Poulsen T, Mantovani A, Mills KHG, Nowak KL, O'Neill LA, Pickkers P, van der Poll T, Ridker PM, Schalkwijk J, Schwartz DA, Siegmund B, Steer CJ, Tilg H, van der Meer JWM, van de Veerdonk FL, Dinarello CA. Netea MG, et al. Among authors: hoffman hm. Nat Immunol. 2017 Jul 19;18(8):826-831. doi: 10.1038/ni.3790. Nat Immunol. 2017. PMID: 28722720 Free PMC article.
Inflammasome-mediated disease animal models reveal roles for innate but not adaptive immunity.
Brydges SD, Mueller JL, McGeough MD, Pena CA, Misaghi A, Gandhi C, Putnam CD, Boyle DL, Firestein GS, Horner AA, Soroosh P, Watford WT, O'Shea JJ, Kastner DL, Hoffman HM. Brydges SD, et al. Among authors: hoffman hm. Immunity. 2009 Jun 19;30(6):875-87. doi: 10.1016/j.immuni.2009.05.005. Epub 2009 Jun 4. Immunity. 2009. PMID: 19501000 Free PMC article.
Constitutively activated NLRP3 inflammasome causes inflammation and abnormal skeletal development in mice.
Bonar SL, Brydges SD, Mueller JL, McGeough MD, Pena C, Chen D, Grimston SK, Hickman-Brecks CL, Ravindran S, McAlinden A, Novack DV, Kastner DL, Civitelli R, Hoffman HM, Mbalaviele G. Bonar SL, et al. Among authors: hoffman hm. PLoS One. 2012;7(4):e35979. doi: 10.1371/journal.pone.0035979. Epub 2012 Apr 27. PLoS One. 2012. PMID: 22558291 Free PMC article.
cASCading specks.
Broderick L, Hoffman HM. Broderick L, et al. Among authors: hoffman hm. Nat Immunol. 2014 Aug;15(8):698-700. doi: 10.1038/ni.2942. Nat Immunol. 2014. PMID: 25045869 No abstract available.
The inflammasomes and autoinflammatory syndromes.
Broderick L, De Nardo D, Franklin BS, Hoffman HM, Latz E. Broderick L, et al. Among authors: hoffman hm. Annu Rev Pathol. 2015;10:395-424. doi: 10.1146/annurev-pathol-012414-040431. Epub 2014 Nov 19. Annu Rev Pathol. 2015. PMID: 25423351 Review.
Alternative splicing regulates stochastic NLRP3 activity.
Hoss F, Mueller JL, Rojas Ringeling F, Rodriguez-Alcazar JF, Brinkschulte R, Seifert G, Stahl R, Broderick L, Putnam CD, Kolodner RD, Canzar S, Geyer M, Hoffman HM, Latz E. Hoss F, et al. Among authors: hoffman hm. Nat Commun. 2019 Jul 19;10(1):3238. doi: 10.1038/s41467-019-11076-1. Nat Commun. 2019. PMID: 31324763 Free PMC article.
183 results